| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/8/2024 | HOL | Baddoo | Acquired via trade | NDF | | After |
| 4/8/2024 | HOL | Castro,MI | Acquired via trade | NDF | | After |
| 4/8/2024 | HOL | Lively | Traded away | NDF | | After |
| 4/8/2024 | HOL | Mullins | Traded away | NDF | | After |
| 4/8/2024 | HOL | Puk | Traded away | NDF | | After |
| 4/8/2024 | HOL | Rooker | Acquired via trade | NDF | | After |
| 4/8/2024 | HOL | Ryu | Acquired via trade | NDF | | After |
| 4/8/2024 | HOL | Saucedo | Acquired via trade | NDF | | After |
| 4/8/2024 | NDF | Baddoo | Traded away | HOL | | After |
| 4/8/2024 | NDF | Castro,MI | Traded away | HOL | | After |
| 4/8/2024 | NDF | Lively | Acquired via trade | HOL | | After |
| 4/8/2024 | NDF | Mullins | Acquired via trade | HOL | | After |
| 4/8/2024 | NDF | Puk | Acquired via trade | HOL | | After |
| 4/8/2024 | NDF | Rooker | Traded away | HOL | | After |
| 4/8/2024 | NDF | Ryu | Traded away | HOL | | After |
| 4/8/2024 | NDF | Saucedo | Traded away | HOL | | After |
| 4/8/2024 | NHP | Megill,Tr | Promoted to active roster | | | Before |
| 4/8/2024 | NHP | Nelson,R | Demoted to reserve roster | | | Before |
| 4/8/2024 | RMH | Castro,W | Placed on Injured List | | 4/8/2024 | Before |
| 4/8/2024 | RMH | Vientos | Promoted to active roster | | | Before |
| 4/14/2024 | CGS | Sale | Placed on Injured List | | 4/9/2024 | Before |
| 4/14/2024 | CGS | Walker,Jor | Promoted to active roster | | | Before |
| 4/14/2024 | HOL | Baddoo | Promoted to active roster | | | Before |
| 4/14/2024 | HOL | Sanchez,J | Placed on Injured List | | 4/14/2024 | Before |
| 4/14/2024 | PRO | Fairchild | Promoted to active roster | | | Before |
| 4/14/2024 | PRO | McCormick | Placed on Injured List | | 4/12/2024 | Before |
| 4/14/2024 | PUE | Lewis,R | Placed on Injured List | | 4/14/2024 | Before |
| 4/14/2024 | PUE | Wisdom | Promoted to active roster | | | Before |
| 4/14/2024 | TOR | Alvarez,Y | Placed on Injured List | | 4/12/2024 | Before |
| 4/14/2024 | TOR | Carpenter,M | Promoted to active roster | | | Before |
| 4/17/2024 | CLE | Ohtani | Placed on Injured List | | 4/15/2024 | Before |
| 4/17/2024 | CLE | White,O | Promoted to active roster | | | Before |
| 4/19/2024 | HAV | Hedges | Traded away | WTB | | After |
| 4/19/2024 | HAV | Hughes | Acquired via trade | WTB | | After |
| 4/19/2024 | WTB | Hedges | Acquired via trade | HAV | | After |
| 4/19/2024 | WTB | Hughes | Traded away | HAV | | After |
| 4/20/2024 | AUR | Manaea | Promoted to active roster | | | Before |
| 4/20/2024 | AUR | Woodruff | Demoted to reserve roster | | | Before |
| 4/20/2024 | DSP | Cimber | Demoted to reserve roster | | | Before |
| 4/20/2024 | DSP | Kopech | Promoted to active roster | | | Before |
| 4/20/2024 | DSP | Littell | Demoted to reserve roster | | | Before |
| 4/20/2024 | OLL | Blackburn | Placed on Injured List | | 4/18/2024 | Before |
| 4/20/2024 | OLL | Fujinami | Demoted to reserve roster | | | Before |
| 4/20/2024 | OLL | Megill,Ty | Promoted to active roster | | | Before |
| 4/20/2024 | OLL | Pearson | Promoted to active roster | | | Before |
| 4/23/2024 | DUR | Ibanez | Placed on Injured List | | 4/22/2024 | Before |
| 4/23/2024 | DUR | Monasterio | Promoted to active roster | | | Before |
| 4/23/2024 | HOL | Castro,MI | Promoted to active roster | | | Before |
| 4/23/2024 | HOL | Holderman | Demoted to reserve roster | | | Before |
| 4/26/2024 | RMH | Florial | Promoted to active roster | | | Before |
| 4/26/2024 | RMH | Kelly,C | Placed on Injured List | | 4/26/2024 | Before |
| 4/29/2024 | HOL | Baddoo | Demoted to reserve roster | | | Before |
| 4/29/2024 | HOL | Sanchez,J | Activated from Injured List | | | Before |
| 4/29/2024 | OLL | Bubic | Promoted to active roster | | | Before |
| 4/29/2024 | OLL | Megill,Ty | Demoted to reserve roster | | | Before |
| 4/29/2024 | OLL | Perez,CE | Placed on Injured List | | 4/28/2024 | Before |
| 4/29/2024 | OLL | Zavala | Promoted to active roster | | | Before |
| 4/29/2024 | TOR | Alvarez,Y | Activated from Injured List | | | Before |
| 4/29/2024 | TOR | Brown,H | Promoted to active roster | | | Before |
| 4/29/2024 | TOR | Carpenter,M | Demoted to reserve roster | | | Before |
| 4/29/2024 | TOR | Manning | Placed on Injured List | | 4/27/2024 | Before |
| 5/2/2024 | CAP | Dominguez,J | Promoted to active roster | | | Before |
| 5/2/2024 | CAP | Hampson | Placed on Injured List | | 4/27/2024 | Before |
| 5/2/2024 | HOL | Eovaldi | Placed on Injured List | | 5/2/2024 | Before |
| 5/2/2024 | HOL | Ryu | Promoted to active roster | | | Before |
| 5/2/2024 | OLL | Miranda | Promoted to active roster | | | Before |
| 5/2/2024 | OLL | Ward,Ta | Placed on Injured List | | 4/30/2024 | Before |
| 5/5/2024 | CAP | Caminero | Promoted to active roster | | | Before |
| 5/5/2024 | CAP | Neto | Placed on Injured List | | 5/4/2024 | Before |
| 5/5/2024 | CLE | Encarnacn-Stran | Demoted to reserve roster | | | Before |
| 5/5/2024 | CLE | Ohtani | Activated from Injured List | | | Before |
| 5/5/2024 | DSP | German | Demoted to reserve roster | | | Before |
| 5/5/2024 | DSP | Littell | Promoted to active roster | | | Before |
| 5/5/2024 | RMH | Castro,W | Activated from Injured List | | | Before |
| 5/5/2024 | RMH | Florial | Demoted to reserve roster | | | Before |
| 5/7/2024 | CAP | Murphy,S | Acquired via trade | CGS | | After |
| 5/7/2024 | CAP | Richards | Acquired via trade | CGS | | After |
| 5/7/2024 | CAP | Wood | Traded away | CGS | | After |
| 5/7/2024 | CGS | Murphy,S | Traded away | CAP | | After |
| 5/7/2024 | CGS | Richards | Traded away | CAP | | After |
| 5/7/2024 | CGS | Wood | Acquired via trade | CAP | | After |
| 5/8/2024 | CAP | Richards | Demoted to reserve roster | | | Before |
| 5/8/2024 | CAP | Ruiz,K | Demoted to reserve roster | | | Before |
| 5/8/2024 | CAP | Winn,K | Promoted to active roster | | | Before |
| 5/8/2024 | CGS | Rodriguez,En | Promoted to active roster | | | Before |
| 5/8/2024 | DSP | Loaisiga | Promoted to active roster | | | Before |
| 5/8/2024 | DSP | Urquidy | Demoted to reserve roster | | | Before |
| 5/8/2024 | OLL | Skubal | Placed on Injured List | | 5/6/2024 | Before |
| 5/8/2024 | OLL | Waldichuk | Promoted to active roster | | | Before |
| 5/8/2024 | RMH | Jimenez,J | Placed on Injured List | | 5/8/2024 | Before |
| 5/8/2024 | RMH | Kelly,C | Activated from Injured List | | | Before |
| 5/8/2024 | RMH | Liberatore | Promoted to active roster | | | Before |
| 5/8/2024 | RMH | Vientos | Demoted to reserve roster | | | Before |
| 5/8/2024 | WTB | Adell | Promoted to active roster | | | Before |
| 5/8/2024 | WTB | Barnhart | Demoted to reserve roster | | | Before |
| 5/8/2024 | WTB | Hedges | Promoted to active roster | | | Before |
| 5/8/2024 | WTB | Yastrzemski | Placed on Injured List | | 5/8/2024 | Before |
| 5/11/2024 | CAP | Fried | Demoted to reserve roster | | | Before |
| 5/11/2024 | CAP | Hampson | Activated from Injured List | | | Before |
| 5/11/2024 | CAP | Ruiz,K | Promoted to active roster | | | Before |
| 5/11/2024 | CAP | Taveras | Placed on Injured List | | 5/9/2024 | Before |
| 5/11/2024 | DUR | Drury | Placed on Injured List | | 5/7/2024 | Before |
| 5/11/2024 | DUR | Ibanez | Activated from Injured List | | | Before |
| 5/14/2024 | CAP | Fried | Promoted to active roster | | | Before |
| 5/14/2024 | CAP | Neto | Activated from Injured List | | | Before |
| 5/14/2024 | CAP | Pivetta | Demoted to reserve roster | | | Before |
| 5/14/2024 | CAP | Ruiz,K | Demoted to reserve roster | | | Before |
| 5/14/2024 | CED | Diaz,Yai | Placed on Injured List | | 5/11/2024 | Before |
| 5/14/2024 | CED | Wallach | Promoted to active roster | | | Before |
| 5/14/2024 | NDF | Diaz,M | Demoted to reserve roster | | | Before |
| 5/14/2024 | NDF | Mikolas | Promoted to active roster | | | Before |
| 5/14/2024 | NHP | Bart | Promoted to active roster | | | Before |
| 5/14/2024 | NHP | Kirk | Placed on Injured List | | 5/13/2024 | Before |
| 5/17/2024 | CAP | Caminero | Demoted to reserve roster | | | Before |
| 5/17/2024 | CAP | Dominguez,J | Demoted to reserve roster | | | Before |
| 5/17/2024 | CAP | Pivetta | Promoted to active roster | | | Before |
| 5/17/2024 | CAP | Rafaela | Promoted to active roster | | | Before |
| 5/17/2024 | CGS | Crawford,K | Placed on Injured List | | 5/8/2024 | Before |
| 5/17/2024 | HOL | Brito | Promoted to active roster | | | Before |
| 5/17/2024 | HOL | Eovaldi | Activated from Injured List | | | Before |
| 5/17/2024 | HOL | Gallo | Demoted to reserve roster | | | Before |
| 5/17/2024 | HOL | Ryu | Demoted to reserve roster | | | Before |
| 5/17/2024 | NHP | Cecconi | Promoted to active roster | | | Before |
| 5/17/2024 | NHP | Morgan | Promoted to active roster | | | Before |
| 5/17/2024 | NHP | Robertson,N | Demoted to reserve roster | | | Before |
| 5/17/2024 | NHP | Verlander | Placed on Injured List | | 5/17/2024 | Before |
| 5/17/2024 | PRO | Mahle | Promoted to active roster | | | Before |
| 5/17/2024 | PRO | Sandoval | Placed on Injured List | | 5/12/2024 | Before |
| 5/17/2024 | RMH | Liberatore | Demoted to reserve roster | | | Before |
| 5/17/2024 | RMH | Montas | Promoted to active roster | | | Before |
| 5/20/2024 | CAP | Rafaela | Demoted to reserve roster | | | Before |
| 5/20/2024 | CAP | Taveras | Activated from Injured List | | | Before |
| 5/20/2024 | CED | Lynch | Promoted to active roster | | | Before |
| 5/20/2024 | CED | Thompson,ZD | Demoted to reserve roster | | | Before |
| 5/20/2024 | NDF | Martini | Demoted to reserve roster | | | Before |
| 5/20/2024 | NDF | Mullins | Promoted to active roster | | | Before |
| 5/20/2024 | OLL | Bubic | Demoted to reserve roster | | | Before |
| 5/20/2024 | OLL | Junis | Demoted to reserve roster | | | Before |
| 5/20/2024 | OLL | McGough | Promoted to active roster | | | Before |
| 5/20/2024 | OLL | Megill,Ty | Promoted to active roster | | | Before |
| 5/20/2024 | OLL | Miranda | Demoted to reserve roster | | | Before |
| 5/20/2024 | OLL | Pearson | Placed on Injured List | | 5/19/2024 | Before |
| 5/20/2024 | OLL | Skubal | Activated from Injured List | | | Before |
| 5/20/2024 | OLL | Ward,Ta | Activated from Injured List | | | Before |
| 5/20/2024 | PUE | Lewis,R | Activated from Injured List | | | Before |
| 5/20/2024 | PUE | Wisdom | Demoted to reserve roster | | | Before |
| 5/20/2024 | TOR | Brown,H | Demoted to reserve roster | | | Before |
| 5/20/2024 | TOR | Greene,H | Promoted to active roster | | | Before |
| 5/20/2024 | TOR | Miller,Br | Demoted to reserve roster | | | Before |
| 5/20/2024 | TOR | Pepiot | Promoted to active roster | | | Before |
| 5/20/2024 | WTB | Jarvis | Demoted to reserve roster | | | Before |
| 5/20/2024 | WTB | Tonkin | Promoted to active roster | | | Before |
| 5/23/2024 | CAP | Fried | Demoted to reserve roster | | | Before |
| 5/23/2024 | CAP | Ruiz,K | Promoted to active roster | | | Before |
| 5/23/2024 | DSP | Cimber | Promoted to active roster | | | Before |
| 5/23/2024 | DSP | German | Promoted to active roster | | | Before |
| 5/23/2024 | DSP | Loaisiga | Demoted to reserve roster | | | Before |
| 5/23/2024 | DSP | May,D | Promoted to active roster | | | Before |
| 5/23/2024 | DSP | Soriano,J | Demoted to reserve roster | | | Before |
| 5/23/2024 | PRO | Fairchild | Demoted to reserve roster | | | Before |
| 5/23/2024 | PRO | McCormick | Activated from Injured List | | | Before |
| 5/26/2024 | CAP | Fried | Promoted to active roster | | | Before |
| 5/26/2024 | CAP | Hall,DL | Demoted to reserve roster | | | Before |
| 5/26/2024 | SPR | Baumann | Promoted to active roster | | | Before |
| 5/26/2024 | SPR | Remillard | Demoted to reserve roster | | | Before |
| 5/29/2024 | AUR | Gray,Jos | Demoted to reserve roster | | | Before |
| 5/29/2024 | AUR | Matz | Demoted to reserve roster | | | Before |
| 5/29/2024 | AUR | Miller,M | Promoted to active roster | | | Before |
| 5/29/2024 | AUR | Woodruff | Promoted to active roster | | | Before |
| 5/29/2024 | CGS | Sale | Activated from Injured List | | | Before |
| 5/29/2024 | NHP | Bart | Demoted to reserve roster | | | Before |
| 5/29/2024 | NHP | Kirk | Activated from Injured List | | | Before |
| 5/29/2024 | NHP | Morgan | Demoted to reserve roster | | | Before |
| 5/29/2024 | NHP | Verlander | Activated from Injured List | | | Before |
| 5/29/2024 | OLL | Blackburn | Activated from Injured List | | | Before |
| 5/29/2024 | OLL | Megill,Ty | Demoted to reserve roster | | | Before |
| 5/29/2024 | OLL | Perez,CE | Activated from Injured List | | | Before |
| 5/29/2024 | OLL | Zavala | Demoted to reserve roster | | | Before |
| 5/29/2024 | PEA | Romano | Placed on Injured List | | 5/29/2024 | Before |
| 5/29/2024 | PEA | Smith-Shawver | Promoted to active roster | | | Before |
| 5/29/2024 | PEA | Toussaint | Placed on Injured List | | 5/28/2024 | Before |
| 5/29/2024 | PEA | Webb,J | Promoted to active roster | | | Before |
| 5/29/2024 | WTB | Adell | Demoted to reserve roster | | | Before |
| 5/29/2024 | WTB | Yastrzemski | Activated from Injured List | | | Before |
| 6/1/2024 | CAP | Dominguez,J | Promoted to active roster | | | Before |
| 6/1/2024 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 6/1/2024 | CED | Carpenter,K | Placed on Injured List | | 5/31/2024 | Before |
| 6/1/2024 | CED | Diaz,Yai | Activated from Injured List | | | Before |
| 6/1/2024 | CED | Lynch | Demoted to reserve roster | | | Before |
| 6/1/2024 | CED | McKenna | Promoted to active roster | | | Before |
| 6/1/2024 | CED | Thompson,K | Promoted to active roster | | | Before |
| 6/1/2024 | CED | Wallach | Demoted to reserve roster | | | Before |
| 6/1/2024 | NDF | Nardi | Placed on Injured List | | 6/1/2024 | Before |
| 6/1/2024 | NDF | Puk | Promoted to active roster | | | Before |
| 6/1/2024 | PUE | Lambert,P | Demoted to reserve roster | | | Before |
| 6/1/2024 | PUE | Wisdom | Promoted to active roster | | | Before |
| 6/4/2024 | SPR | Houser | Demoted to reserve roster | | | Before |
| 6/4/2024 | SPR | Rodriguez,G | Promoted to active roster | | | Before |
| 6/4/2024 | TOR | Brown,H | Promoted to active roster | | | Before |
| 6/4/2024 | TOR | Manning | Activated from Injured List | | | Before |
| 6/4/2024 | TOR | Manning | Demoted to reserve roster | | | Before |
| 6/4/2024 | TOR | Miller,Br | Promoted to active roster | | | Before |
| 6/4/2024 | TOR | Pepiot | Demoted to reserve roster | | | Before |
| 6/4/2024 | TOR | Suarez,Ro | Demoted to reserve roster | | | Before |
| 6/6/2024 | AUR | Hader | Traded away | CLE | | After |
| 6/6/2024 | AUR | Moll | Traded away | CLE | | After |
| 6/6/2024 | AUR | Pressly | Traded away | CLE | | After |
| 6/6/2024 | AUR | Steele | Acquired via trade | CLE | | After |
| 6/6/2024 | AUR | Woodruff | Traded away | CLE | | After |
| 6/6/2024 | CLE | Hader | Acquired via trade | AUR | | After |
| 6/6/2024 | CLE | Moll | Acquired via trade | AUR | | After |
| 6/6/2024 | CLE | Pressly | Acquired via trade | AUR | | After |
| 6/6/2024 | CLE | Steele | Traded away | AUR | | After |
| 6/6/2024 | CLE | Woodruff | Acquired via trade | AUR | | After |
| 6/7/2024 | AUR | Erceg | Promoted to active roster | | | Before |
| 6/7/2024 | AUR | Gray,Jos | Promoted to active roster | | | Before |
| 6/7/2024 | AUR | Matz | Promoted to active roster | | | Before |
| 6/7/2024 | CLE | Lodolo | Demoted to reserve roster | | | Before |
| 6/7/2024 | CLE | Moniak | Placed on Injured List | | 6/3/2024 | Before |
| 6/7/2024 | CLE | White,O | Demoted to reserve roster | | | Before |
| 6/7/2024 | CUY | Arias | Placed on Injured List | | 6/5/2024 | Before |
| 6/7/2024 | CUY | Fletcher,Do | Signed | | | Before |
| 6/7/2024 | CUY | Funderburk | Promoted to active roster | | | Before |
| 6/7/2024 | CUY | Marte,N | Promoted to active roster | | | Before |
| 6/7/2024 | CUY | Miller,S | Demoted to reserve roster | | | Before |
| 6/7/2024 | CUY | Thomas,A | Demoted to reserve roster | | | Before |
| 6/7/2024 | DUR | Drury | Activated from Injured List | | | Before |
| 6/7/2024 | DUR | Monasterio | Demoted to reserve roster | | | Before |
| 6/9/2024 | NDF | Honeywell | Acquired via trade | OLL | | After |
| 6/9/2024 | NDF | Jansen,K | Acquired via trade | OLL | | After |
| 6/9/2024 | NDF | Montgomery | Acquired via trade | OLL | | After |
| 6/9/2024 | NDF | Rodon | Traded away | OLL | | After |
| 6/9/2024 | NDF | Stanton | Traded away | OLL | | After |
| 6/9/2024 | NDF | Weathers | Traded away | OLL | | After |
| 6/9/2024 | OLL | Honeywell | Traded away | NDF | | After |
| 6/9/2024 | OLL | Jansen,K | Traded away | NDF | | After |
| 6/9/2024 | OLL | Montgomery | Traded away | NDF | | After |
| 6/9/2024 | OLL | Rodon | Acquired via trade | NDF | | After |
| 6/9/2024 | OLL | Stanton | Acquired via trade | NDF | | After |
| 6/9/2024 | OLL | Weathers | Acquired via trade | NDF | | After |
| 6/10/2024 | AUR | Baker,B | Demoted to reserve roster | | | Before |
| 6/10/2024 | AUR | Blanco,D | Demoted to reserve roster | | | Before |
| 6/10/2024 | AUR | Call | Promoted to active roster | | | Before |
| 6/10/2024 | AUR | Perdomo,A | Promoted to active roster | | | Before |
| 6/10/2024 | DSP | Cimber | Demoted to reserve roster | | | Before |
| 6/10/2024 | DSP | Loaisiga | Promoted to active roster | | | Before |
| 6/10/2024 | DSP | Rea | Demoted to reserve roster | | | Before |
| 6/10/2024 | DSP | Urquidy | Promoted to active roster | | | Before |
| 6/10/2024 | NDF | Jansen,K | Demoted to reserve roster | | | Before |
| 6/10/2024 | NDF | Kelly,Mi | Demoted to reserve roster | | | Before |
| 6/10/2024 | OLL | Brieske | Demoted to reserve roster | | | Before |
| 6/10/2024 | OLL | Fujinami | Promoted to active roster | | | Before |
| 6/10/2024 | OLL | Pearson | Activated from Injured List | | | Before |
| 6/10/2024 | OLL | Rodon | Promoted to active roster | | | Before |
| 6/10/2024 | OLL | Stanton | Demoted to reserve roster | | | Before |
| 6/10/2024 | OLL | Stanton | Promoted to active roster | | | Before |
| 6/10/2024 | OLL | Weathers | Demoted to reserve roster | | | Before |
| 6/10/2024 | OLL | Weathers | Promoted to active roster | | | Before |
| 6/10/2024 | RMH | Calhoun,W | Promoted to active roster | | | Before |
| 6/10/2024 | RMH | Ford | Demoted to reserve roster | | | Before |
| 6/10/2024 | RMH | Jimenez,J | Activated from Injured List | | | Before |
| 6/10/2024 | RMH | Montas | Demoted to reserve roster | | | Before |
| 6/13/2024 | CAP | Dominguez,J | Demoted to reserve roster | | | Before |
| 6/13/2024 | CAP | Fried | Placed on Injured List | | 6/11/2024 | Before |
| 6/13/2024 | CAP | Hall,DL | Promoted to active roster | | | Before |
| 6/13/2024 | CAP | Harrison,K | Promoted to active roster | | | Before |
| 6/13/2024 | DSP | May,D | Demoted to reserve roster | | | Before |
| 6/13/2024 | DSP | Rea | Promoted to active roster | | | Before |
| 6/13/2024 | NDF | Francis,B | Demoted to reserve roster | | | Before |
| 6/13/2024 | NDF | Refsnyder | Promoted to active roster | | | Before |
| 6/15/2024 | CGS | Crawford,K | Traded away | TOR | | After |
| 6/15/2024 | TOR | Crawford,K | Acquired via trade | CGS | | After |
| 6/16/2024 | CAP | Baez | Promoted to active roster | | | Before |
| 6/16/2024 | CAP | Hall,DL | Demoted to reserve roster | | | Before |
| 6/16/2024 | CAP | Hampson | Demoted to reserve roster | | | Before |
| 6/16/2024 | CAP | Peraza | Promoted to active roster | | | Before |
| 6/16/2024 | CAP | Priester | Promoted to active roster | | | Before |
| 6/16/2024 | CAP | Richards | Promoted to active roster | | | Before |
| 6/16/2024 | CAP | Story | Promoted to active roster | | | Before |
| 6/16/2024 | CAP | Taylor,T | Demoted to reserve roster | | | Before |
| 6/16/2024 | CAP | Williams,G | Demoted to reserve roster | | | Before |
| 6/16/2024 | CAP | Winn,K | Demoted to reserve roster | | | Before |
| 6/16/2024 | CED | Carpenter,K | Activated from Injured List | | | Before |
| 6/16/2024 | CED | McKenna | Demoted to reserve roster | | | Before |
| 6/16/2024 | PUE | Hudson,Dak | Promoted to active roster | | | Before |
| 6/16/2024 | PUE | O'Hearn | Demoted to reserve roster | | | Before |
| 6/16/2024 | SPR | Allen.L | Placed on Injured List | | 6/7/2024 | Before |
| 6/16/2024 | SPR | Irvin,C | Promoted to active roster | | | Before |
| 6/16/2024 | TOR | Crawford,K | Activated from Injured List | | | Before |
| 6/16/2024 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 6/19/2024 | DUR | Law | Promoted to active roster | | | Before |
| 6/19/2024 | DUR | Springs | Demoted to reserve roster | | | Before |
| 6/19/2024 | NHP | Jackson,J | Demoted to reserve roster | | | Before |
| 6/19/2024 | NHP | Stewart,B | Promoted to active roster | | | Before |
| 6/19/2024 | PRO | Mahle | Placed on Injured List | | 6/19/2024 | Before |
| 6/19/2024 | PRO | Sandoval | Activated from Injured List | | | Before |
| 6/19/2024 | TOR | Greene,H | Promoted to active roster | | | Before |
| 6/19/2024 | TOR | Kelly,J | Placed on Injured List | | 6/19/2024 | Before |
| 6/19/2024 | WTB | Cortes | Demoted to reserve roster | | | Before |
| 6/19/2024 | WTB | Means | Promoted to active roster | | | Before |
| 6/22/2024 | DSP | Cimber | Promoted to active roster | | | Before |
| 6/22/2024 | DSP | Loaisiga | Placed on Injured List | | 6/22/2024 | Before |
| 6/22/2024 | NDF | Stewart,DJ | Placed on Injured List | | 6/17/2024 | Before |
| 6/22/2024 | NDF | Urias,R | Promoted to active roster | | | Before |
| 6/22/2024 | OLL | Kelenic | Placed on Injured List | | 6/21/2024 | Before |
| 6/22/2024 | OLL | Stanton | Promoted to active roster | | | Before |
| 6/22/2024 | SPR | Allen.L | Activated from Injured List | | | Before |
| 6/22/2024 | SPR | Baumann | Demoted to reserve roster | | | Before |
| 6/22/2024 | SPR | Maton,P | Placed on Injured List | | 6/22/2024 | Before |
| 6/22/2024 | SPR | Sands | Promoted to active roster | | | Before |
| 6/25/2024 | CAP | Cowser | Promoted to active roster | | | Before |
| 6/25/2024 | CAP | Herrera,I | Promoted to active roster | | | Before |
| 6/25/2024 | CAP | Murphy,S | Placed on Injured List | | 6/23/2024 | Before |
| 6/25/2024 | CAP | Neto | Placed on Injured List | | 6/24/2024 | Before |
| 6/25/2024 | DSP | Azocar | Promoted to active roster | | | Before |
| 6/25/2024 | DSP | Cimber | Demoted to reserve roster | | | Before |
| 6/25/2024 | DSP | Delay | Promoted to active roster | | | Before |
| 6/25/2024 | DSP | Haniger | Demoted to reserve roster | | | Before |
| 6/25/2024 | DSP | Hicks,A | Demoted to reserve roster | | | Before |
| 6/25/2024 | DSP | Hilliard | Promoted to active roster | | | Before |
| 6/25/2024 | DSP | Mejia,F | Demoted to reserve roster | | | Before |
| 6/25/2024 | DSP | Peterson,J | Demoted to reserve roster | | | Before |
| 6/25/2024 | DSP | Schoop | Promoted to active roster | | | Before |
| 6/25/2024 | DSP | Soriano,J | Promoted to active roster | | | Before |
| 6/25/2024 | DUR | Musgrove | Placed on Injured List | | 6/22/2024 | Before |
| 6/25/2024 | DUR | Woo | Promoted to active roster | | | Before |
| 6/25/2024 | PUE | Marsh,B | Placed on Injured List | | 6/24/2024 | Before |
| 6/25/2024 | PUE | Robles | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Baez | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Caminero | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Cowser | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Hall,DL | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Hampson | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Harrison,K | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Peraza | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Priester | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Story | Demoted to reserve roster | | | Before |
| 6/28/2024 | CAP | Taylor,T | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Williams,G | Promoted to active roster | | | Before |
| 6/28/2024 | CAP | Winn,K | Promoted to active roster | | | Before |
| 6/28/2024 | HOL | Castro,MI | Demoted to reserve roster | | | Before |
| 6/28/2024 | HOL | Saucedo | Promoted to active roster | | | Before |
| 6/30/2024 | DUR | Kelly,J | Acquired via trade | TOR | | After |
| 6/30/2024 | DUR | McCann | Acquired via trade | TOR | | After |
| 6/30/2024 | DUR | Murphy,T | Traded away | TOR | | After |
| 6/30/2024 | TOR | Kelly,J | Traded away | DUR | | After |
| 6/30/2024 | TOR | McCann | Traded away | DUR | | After |
| 6/30/2024 | TOR | Murphy,T | Acquired via trade | DUR | | After |
| 7/1/2024 | DUR | McCann | Demoted to reserve roster | | | Before |
| 7/1/2024 | NHP | Madrigal | Promoted to active roster | | | Before |
| 7/1/2024 | NHP | Velazquez,N | Demoted to reserve roster | | | Before |
| 7/1/2024 | PUE | Robles | Placed on Injured List | | 6/30/2024 | Before |
| 7/1/2024 | PUE | Young,JS | Promoted to active roster | | | Before |
| 7/1/2024 | SPR | Baumann | Promoted to active roster | | | Before |
| 7/1/2024 | SPR | De La Cruz,B | Demoted to reserve roster | | | Before |
| 7/1/2024 | SPR | Irvin,C | Demoted to reserve roster | | | Before |
| 7/1/2024 | SPR | Irvin,C | Promoted to active roster | | | Before |
| 7/1/2024 | TOR | Murphy,T | Promoted to active roster | | | Before |
| 7/4/2024 | SPR | Gipson-Long | Demoted to reserve roster | | | Before |
| 7/4/2024 | SPR | Maton,P | Activated from Injured List | | | Before |
| 7/4/2024 | TOR | Brown,H | Demoted to reserve roster | | | Before |
| 7/4/2024 | TOR | Manning | Promoted to active roster | | | Before |
| 7/7/2024 | CLE | Arroyo | Demoted to reserve roster | | | Before |
| 7/7/2024 | CLE | Moniak | Activated from Injured List | | | Before |
| 7/7/2024 | CUY | Arias | Activated from Injured List | | | Before |
| 7/7/2024 | CUY | Armstrong | Demoted to reserve roster | | | Before |
| 7/7/2024 | CUY | Funderburk | Demoted to reserve roster | | | Before |
| 7/7/2024 | CUY | Kirilloff | Demoted to reserve roster | | | Before |
| 7/7/2024 | CUY | Loftin | Promoted to active roster | | | Before |
| 7/7/2024 | CUY | Marte,N | Demoted to reserve roster | | | Before |
| 7/7/2024 | CUY | Miller,S | Promoted to active roster | | | Before |
| 7/7/2024 | CUY | Palencia | Promoted to active roster | | | Before |
| 7/9/2024 | AUR | Bogaerts | Traded away | CUY | | After |
| 7/9/2024 | AUR | Calhoun,W | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Contreras | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Curry | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Dahl | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Foley | Traded away | RMH | | After |
| 7/9/2024 | AUR | Gonzales,M | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Grandal | Traded away | RMH | | After |
| 7/9/2024 | AUR | Gray,Jon | Acquired via trade | TOR | | After |
| 7/9/2024 | AUR | Javier | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Jimenez,J | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Kelly,C | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Larnach | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Montas | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Moore,D | Traded away | TOR | | After |
| 7/9/2024 | AUR | Moore,D | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Nimmo | Traded away | CUY | | After |
| 7/9/2024 | AUR | Ortiz,LL | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Santander | Acquired via trade | TOR | | After |
| 7/9/2024 | AUR | Steele | Traded away | RMH | | After |
| 7/9/2024 | AUR | Thompson,M | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Trejo | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Vientos | Acquired via trade | RMH | | After |
| 7/9/2024 | AUR | Yelich | Traded away | TOR | | After |
| 7/9/2024 | AUR | Yelich | Acquired via trade | CUY | | After |
| 7/9/2024 | AUR | Yepez | Acquired via trade | RMH | | After |
| 7/9/2024 | CUY | Bogaerts | Acquired via trade | AUR | | After |
| 7/9/2024 | CUY | Curry | Traded away | AUR | | After |
| 7/9/2024 | CUY | Larnach | Traded away | AUR | | After |
| 7/9/2024 | CUY | Moore,D | Traded away | AUR | | After |
| 7/9/2024 | CUY | Nimmo | Acquired via trade | AUR | | After |
| 7/9/2024 | CUY | Thompson,M | Traded away | AUR | | After |
| 7/9/2024 | CUY | Trejo | Traded away | AUR | | After |
| 7/9/2024 | CUY | Yelich | Traded away | AUR | | After |
| 7/9/2024 | RMH | Calhoun,W | Traded away | AUR | | After |
| 7/9/2024 | RMH | Contreras | Traded away | AUR | | After |
| 7/9/2024 | RMH | Dahl | Traded away | AUR | | After |
| 7/9/2024 | RMH | Foley | Acquired via trade | AUR | | After |
| 7/9/2024 | RMH | Gonzales,M | Traded away | AUR | | After |
| 7/9/2024 | RMH | Grandal | Acquired via trade | AUR | | After |
| 7/9/2024 | RMH | Javier | Traded away | AUR | | After |
| 7/9/2024 | RMH | Jimenez,J | Traded away | AUR | | After |
| 7/9/2024 | RMH | Kelly,C | Traded away | AUR | | After |
| 7/9/2024 | RMH | Montas | Traded away | AUR | | After |
| 7/9/2024 | RMH | Ortiz,LL | Traded away | AUR | | After |
| 7/9/2024 | RMH | Steele | Acquired via trade | AUR | | After |
| 7/9/2024 | RMH | Vientos | Traded away | AUR | | After |
| 7/9/2024 | RMH | Yepez | Traded away | AUR | | After |
| 7/9/2024 | TOR | Gray,Jon | Traded away | AUR | | After |
| 7/9/2024 | TOR | Moore,D | Acquired via trade | AUR | | After |
| 7/9/2024 | TOR | Santander | Traded away | AUR | | After |
| 7/9/2024 | TOR | Yelich | Acquired via trade | AUR | | After |
| 7/10/2024 | AUR | Baker,B | Promoted to active roster | | | Before |
| 7/10/2024 | AUR | Calhoun,W | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Erceg | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Gray,Jon | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Gray,Jon | Promoted to active roster | | | Before |
| 7/10/2024 | AUR | Javier | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Javier | Promoted to active roster | | | Before |
| 7/10/2024 | AUR | Jimenez,J | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Jimenez,J | Promoted to active roster | | | Before |
| 7/10/2024 | AUR | Kelly,C | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Larnach | Promoted to active roster | | | Before |
| 7/10/2024 | AUR | Matz | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Santander | Demoted to reserve roster | | | Before |
| 7/10/2024 | AUR | Santander | Promoted to active roster | | | Before |
| 7/10/2024 | CAP | Fried | Activated from Injured List | | | Before |
| 7/10/2024 | CAP | Hall,DL | Demoted to reserve roster | | | Before |
| 7/10/2024 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 7/10/2024 | CAP | Murphy,S | Activated from Injured List | | | Before |
| 7/10/2024 | CED | Arenado | Placed on Injured List | | 7/8/2024 | Before |
| 7/10/2024 | CED | Smith,K | Promoted to active roster | | | Before |
| 7/10/2024 | CUY | Fletcher,Do | Demoted to reserve roster | | | Before |
| 7/10/2024 | CUY | Kirilloff | Promoted to active roster | | | Before |
| 7/10/2024 | NHP | Romero | Demoted to reserve roster | | | Before |
| 7/10/2024 | NHP | Strzelecki | Promoted to active roster | | | Before |
| 7/10/2024 | RMH | Ford | Promoted to active roster | | | Before |
| 7/10/2024 | RMH | Grandal | Promoted to active roster | | | Before |
| 7/13/2024 | AUR | Bouchard | Promoted to active roster | | | Before |
| 7/13/2024 | AUR | Curry | Promoted to active roster | | | Before |
| 7/13/2024 | AUR | Gurriel,L | Placed on Injured List | | 7/13/2024 | Before |
| 7/13/2024 | AUR | Jimenez,J | Placed on Injured List | | 7/13/2024 | Before |
| 7/13/2024 | CAP | Fried | Demoted to reserve roster | | | Before |
| 7/13/2024 | CAP | Harrison,K | Promoted to active roster | | | Before |
| 7/13/2024 | CAP | Priester | Promoted to active roster | | | Before |
| 7/13/2024 | CAP | Williams,G | Demoted to reserve roster | | | Before |
| 7/13/2024 | DSP | Littell | Placed on Injured List | | 7/12/2024 | Before |
| 7/13/2024 | DSP | May,D | Promoted to active roster | | | Before |
| 7/13/2024 | DUR | Kelly,J | Activated from Injured List | | | Before |
| 7/13/2024 | DUR | Quintana | Demoted to reserve roster | | | Before |
| 7/13/2024 | DUR | Thompson,R | Demoted to reserve roster | | | Before |
| 7/13/2024 | DUR | Velasquez | Promoted to active roster | | | Before |
| 7/13/2024 | HOL | Ryu | Promoted to active roster | | | Before |
| 7/13/2024 | HOL | Scherzer | Placed on Injured List | | 7/13/2024 | Before |
| 7/13/2024 | NDF | Avila | Promoted to active roster | | | Before |
| 7/13/2024 | NDF | Butto | Demoted to reserve roster | | | Before |
| 7/13/2024 | NDF | Cleavinger | Demoted to reserve roster | | | Before |
| 7/13/2024 | NDF | Garcia,Ro | Demoted to reserve roster | | | Before |
| 7/13/2024 | NDF | Nardi | Activated from Injured List | | | Before |
| 7/13/2024 | NDF | Stewart,DJ | Activated from Injured List | | | Before |
| 7/15/2024 | CGS | Belt | Traded away | RMH | | After |
| 7/15/2024 | CGS | Liberatore | Acquired via trade | RMH | | After |
| 7/15/2024 | CGS | Medina | Acquired via trade | RMH | | After |
| 7/15/2024 | HOL | Castro,MI | Traded away | WTB | | After |
| 7/15/2024 | HOL | Cole | Acquired via trade | WTB | | After |
| 7/15/2024 | HOL | Fletcher,Da | Traded away | WTB | | After |
| 7/15/2024 | HOL | Means | Acquired via trade | WTB | | After |
| 7/15/2024 | HOL | Ryu | Traded away | WTB | | After |
| 7/15/2024 | HOL | Saucedo | Traded away | WTB | | After |
| 7/15/2024 | HOL | Scherzer | Traded away | WTB | | After |
| 7/15/2024 | RMH | Belt | Acquired via trade | CGS | | After |
| 7/15/2024 | RMH | Liberatore | Traded away | CGS | | After |
| 7/15/2024 | RMH | Medina | Traded away | CGS | | After |
| 7/15/2024 | WTB | Castro,MI | Acquired via trade | HOL | | After |
| 7/15/2024 | WTB | Cole | Traded away | HOL | | After |
| 7/15/2024 | WTB | Fletcher,Da | Acquired via trade | HOL | | After |
| 7/15/2024 | WTB | Means | Traded away | HOL | | After |
| 7/15/2024 | WTB | Ryu | Acquired via trade | HOL | | After |
| 7/15/2024 | WTB | Saucedo | Acquired via trade | HOL | | After |
| 7/15/2024 | WTB | Scherzer | Acquired via trade | HOL | | After |
| 7/16/2024 | RMH | Montero,E | Demoted to reserve roster | | | Before |
| 7/18/2024 | CLE | Alzolay | Acquired via trade | OLL | | After |
| 7/18/2024 | CLE | Ashcraft | Traded away | OLL | | After |
| 7/18/2024 | CLE | Espinal | Acquired via trade | DUR | | After |
| 7/18/2024 | DUR | Espinal | Traded away | CLE | | After |
| 7/18/2024 | HAV | Anderson,Ti | Acquired via trade | OLL | | After |
| 7/18/2024 | HAV | Cordero,J | Traded away | HOL | | After |
| 7/18/2024 | HAV | deGrom | Traded away | OLL | | After |
| 7/18/2024 | HAV | Junis | Acquired via trade | OLL | | After |
| 7/18/2024 | HAV | Pearson | Acquired via trade | OLL | | After |
| 7/18/2024 | HAV | Perez,S | Acquired via trade | OLL | | After |
| 7/18/2024 | HOL | Canario | Traded away | OLL | | After |
| 7/18/2024 | HOL | Canning | Acquired via trade | OLL | | After |
| 7/18/2024 | HOL | Cordero,J | Acquired via trade | HAV | | After |
| 7/18/2024 | OLL | Alzolay | Traded away | CLE | | After |
| 7/18/2024 | OLL | Anderson,Ti | Traded away | HAV | | After |
| 7/18/2024 | OLL | Ashcraft | Acquired via trade | CLE | | After |
| 7/18/2024 | OLL | Canario | Acquired via trade | HOL | | After |
| 7/18/2024 | OLL | Canning | Traded away | HOL | | After |
| 7/18/2024 | OLL | deGrom | Acquired via trade | HAV | | After |
| 7/18/2024 | OLL | Junis | Traded away | HAV | | After |
| 7/18/2024 | OLL | Pearson | Traded away | HAV | | After |
| 7/18/2024 | OLL | Perez,S | Traded away | HAV | | After |
| 7/19/2024 | CGS | Medina | Promoted to active roster | | | Before |
| 7/19/2024 | CGS | Sale | Placed on Injured List | | 7/3/2024 | Before |
| 7/19/2024 | CGS | Soderstrom | Promoted to active roster | | | Before |
| 7/19/2024 | CLE | Bradley,T | Demoted to reserve roster | | | Before |
| 7/19/2024 | CLE | Espinal | Promoted to active roster | | | Before |
| 7/19/2024 | HOL | Holderman | Promoted to active roster | | | Before |
| 7/19/2024 | HOL | Means | Demoted to reserve roster | | | Before |
| 7/19/2024 | NHP | Cecconi | Demoted to reserve roster | | | Before |
| 7/19/2024 | NHP | Waldron | Promoted to active roster | | | Before |
| 7/19/2024 | OLL | deGrom | Demoted to reserve roster | | | Before |
| 7/19/2024 | OLL | Kelenic | Activated from Injured List | | | Before |
| 7/19/2024 | OLL | Megill,Ty | Promoted to active roster | | | Before |
| 7/19/2024 | OLL | Patino | Promoted to active roster | | | Before |
| 7/19/2024 | OLL | Zavala | Promoted to active roster | | | Before |
| 7/22/2024 | CAP | Cruz,O | Promoted to active roster | | | Before |
| 7/22/2024 | CAP | Hall,DL | Promoted to active roster | | | Before |
| 7/22/2024 | CAP | Pasquantino | Demoted to reserve roster | | | Before |
| 7/22/2024 | CAP | Peraza | Promoted to active roster | | | Before |
| 7/22/2024 | CAP | Pivetta | Placed on Injured List | | 7/15/2024 | Before |
| 7/22/2024 | CAP | Taylor,T | Demoted to reserve roster | | | Before |
| 7/22/2024 | CED | Arenado | Activated from Injured List | | | Before |
| 7/22/2024 | CED | McKenna | Promoted to active roster | | | Before |
| 7/22/2024 | CED | Smith,K | Demoted to reserve roster | | | Before |
| 7/22/2024 | CED | Thompson,K | Demoted to reserve roster | | | Before |
| 7/22/2024 | CLE | Vierling | Demoted to reserve roster | | | Before |
| 7/22/2024 | CLE | Vierling | Promoted to active roster | | | Before |
| 7/22/2024 | CUY | Flaherty | Promoted to active roster | | | Before |
| 7/22/2024 | CUY | Garrett,B | Placed on Injured List | | 7/22/2024 | Before |
| 7/22/2024 | DSP | Azocar | Demoted to reserve roster | | | Before |
| 7/22/2024 | DSP | Haniger | Promoted to active roster | | | Before |
| 7/22/2024 | DSP | Hicks,A | Promoted to active roster | | | Before |
| 7/22/2024 | DSP | Hilliard | Demoted to reserve roster | | | Before |
| 7/22/2024 | DSP | Hilliard | Promoted to active roster | | | Before |
| 7/22/2024 | DSP | Suwinski | Placed on Injured List | | 7/22/2024 | Before |
| 7/22/2024 | HAV | Anderson,Ti | Demoted to reserve roster | | | Before |
| 7/22/2024 | HAV | Jackson,Z | Demoted to reserve roster | | | Before |
| 7/22/2024 | HAV | Junis | Promoted to active roster | | | Before |
| 7/22/2024 | HOL | Canning | Demoted to reserve roster | | | Before |
| 7/22/2024 | HOL | Cordero,J | Demoted to reserve roster | | | Before |
| 7/22/2024 | NDF | Jackson,L | Demoted to reserve roster | | | Before |
| 7/22/2024 | NDF | Jansen,K | Promoted to active roster | | | Before |
| 7/22/2024 | PUE | Burleson | Promoted to active roster | | | Before |
| 7/22/2024 | PUE | Campbell | Demoted to reserve roster | | | Before |
| 7/22/2024 | PUE | Hudson,Dak | Demoted to reserve roster | | | Before |
| 7/22/2024 | PUE | Lambert,P | Promoted to active roster | | | Before |
| 7/22/2024 | PUE | Marsh,B | Activated from Injured List | | | Before |
| 7/22/2024 | PUE | Mlodzinski | Promoted to active roster | | | Before |
| 7/22/2024 | PUE | Ramirez,N | Demoted to reserve roster | | | Before |
| 7/22/2024 | PUE | Saalfrank | Promoted to active roster | | | Before |
| 7/22/2024 | PUE | Schwarber | Demoted to reserve roster | | | Before |
| 7/22/2024 | PUE | Wisdom | Demoted to reserve roster | | | Before |
| 7/22/2024 | TOR | Brown,H | Promoted to active roster | | | Before |
| 7/22/2024 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 7/22/2024 | TOR | Hendricks | Demoted to reserve roster | | | Before |
| 7/22/2024 | TOR | Suarez,Ro | Promoted to active roster | | | Before |
| 7/25/2024 | AUR | Bouchard | Demoted to reserve roster | | | Before |
| 7/25/2024 | AUR | Curry | Placed on Injured List | | 7/19/2024 | Before |
| 7/25/2024 | AUR | Gurriel,L | Activated from Injured List | | | Before |
| 7/25/2024 | AUR | Jimenez,J | Activated from Injured List | | | Before |
| 7/25/2024 | CAP | Cabrera,E | Placed on Injured List | | 7/24/2024 | Before |
| 7/25/2024 | CAP | Caminero | Demoted to reserve roster | | | Before |
| 7/25/2024 | CAP | Cruz,O | Demoted to reserve roster | | | Before |
| 7/25/2024 | CAP | Fried | Promoted to active roster | | | Before |
| 7/25/2024 | CAP | Hall,DL | Demoted to reserve roster | | | Before |
| 7/25/2024 | CAP | Herrera,I | Promoted to active roster | | | Before |
| 7/25/2024 | CAP | Murphy,S | Placed on Injured List | | 7/25/2024 | Before |
| 7/25/2024 | CAP | Pasquantino | Promoted to active roster | | | Before |
| 7/25/2024 | CAP | Peraza | Demoted to reserve roster | | | Before |
| 7/25/2024 | CAP | Pivetta | Activated from Injured List | | | Before |
| 7/25/2024 | CAP | Taylor,T | Promoted to active roster | | | Before |
| 7/25/2024 | CAP | Williams,G | Promoted to active roster | | | Before |
| 7/25/2024 | CAP | Winn,K | Demoted to reserve roster | | | Before |
| 7/25/2024 | CED | Lynch | Promoted to active roster | | | Before |
| 7/25/2024 | CED | McKenna | Demoted to reserve roster | | | Before |
| 7/25/2024 | CED | Miller,Bo | Placed on Injured List | | 7/23/2024 | Before |
| 7/25/2024 | CED | Thompson,K | Promoted to active roster | | | Before |
| 7/25/2024 | CLE | Carter | Promoted to active roster | | | Before |
| 7/25/2024 | CLE | Raley,L | Demoted to reserve roster | | | Before |
| 7/25/2024 | DSP | Boyle | Promoted to active roster | | | Before |
| 7/25/2024 | DSP | May,D | Demoted to reserve roster | | | Before |
| 7/25/2024 | HAV | Abreu,W | Promoted to active roster | | | Before |
| 7/25/2024 | HAV | Caballero | Demoted to reserve roster | | | Before |
| 7/25/2024 | HAV | Diaz,Aled | Promoted to active roster | | | Before |
| 7/25/2024 | HAV | Lopez,N | Demoted to reserve roster | | | Before |
| 7/25/2024 | HAV | Moncada | Promoted to active roster | | | Before |
| 7/25/2024 | HAV | Rivera | Demoted to reserve roster | | | Before |
| 7/28/2024 | CUY | Armstrong | Promoted to active roster | | | Before |
| 7/28/2024 | CUY | Fletcher,Do | Promoted to active roster | | | Before |
| 7/28/2024 | CUY | Kirilloff | Placed on Injured List | | 7/25/2024 | Before |
| 7/28/2024 | CUY | Marte,N | Promoted to active roster | | | Before |
| 7/28/2024 | CUY | Palencia | Demoted to reserve roster | | | Before |
| 7/28/2024 | CUY | Walls | Demoted to reserve roster | | | Before |
| 7/28/2024 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 7/28/2024 | DSP | Cimber | Promoted to active roster | | | Before |
| 7/28/2024 | DSP | Littell | Activated from Injured List | | | Before |
| 7/28/2024 | DSP | Rea | Demoted to reserve roster | | | Before |
| 7/28/2024 | HOL | Canning | Promoted to active roster | | | Before |
| 7/28/2024 | HOL | Ragans | Demoted to reserve roster | | | Before |
| 7/31/2024 | CAP | Dominguez,J | Promoted to active roster | | | Before |
| 7/31/2024 | CAP | Taylor,T | Demoted to reserve roster | | | Before |
| 7/31/2024 | DSP | Cimber | Demoted to reserve roster | | | Before |
| 7/31/2024 | DSP | Loaisiga | Activated from Injured List | | | Before |
| 7/31/2024 | WTB | Nevin | Promoted to active roster | | | Before |
| 7/31/2024 | WTB | Wantz | Demoted to reserve roster | | | Before |
| 8/3/2024 | CAP | Cabrera,E | Activated from Injured List | | | Before |
| 8/3/2024 | CAP | Priester | Demoted to reserve roster | | | Before |
| 8/3/2024 | CED | Arenado | Placed on Injured List | | 8/2/2024 | Before |
| 8/3/2024 | CED | Carpenter,K | Placed on Injured List | | 8/1/2024 | Before |
| 8/3/2024 | CED | McKenna | Promoted to active roster | | | Before |
| 8/3/2024 | CED | Miller,Bo | Activated from Injured List | | | Before |
| 8/3/2024 | CED | Perez,E | Demoted to reserve roster | | | Before |
| 8/3/2024 | CED | Smith,K | Promoted to active roster | | | Before |
| 8/3/2024 | DSP | Hilliard | Demoted to reserve roster | | | Before |
| 8/3/2024 | DSP | Suwinski | Activated from Injured List | | | Before |
| 8/3/2024 | DUR | Lyles | Placed on Injured List | | 7/30/2024 | Before |
| 8/3/2024 | DUR | Paddack | Promoted to active roster | | | Before |
| 8/3/2024 | NHP | Anderson,N | Demoted to reserve roster | | | Before |
| 8/3/2024 | NHP | Morgan | Promoted to active roster | | | Before |
| 8/3/2024 | NHP | Nelson,R | Promoted to active roster | | | Before |
| 8/3/2024 | NHP | Verlander | Placed on Injured List | | 8/2/2024 | Before |
| 8/6/2024 | CAP | Neto | Activated from Injured List | | | Before |
| 8/6/2024 | DSP | Boyle | Promoted to active roster | | | Before |
| 8/6/2024 | DSP | Kopech | Demoted to reserve roster | | | Before |
| 8/6/2024 | DSP | Lynn | Demoted to reserve roster | | | Before |
| 8/6/2024 | DSP | May,D | Promoted to active roster | | | Before |
| 8/6/2024 | DSP | Peterson,J | Promoted to active roster | | | Before |
| 8/6/2024 | DSP | Urias,L | Placed on Injured List | | 8/6/2024 | Before |
| 8/6/2024 | NHP | Hurt | Promoted to active roster | | | Before |
| 8/6/2024 | NHP | Nelson,R | Placed on Injured List | | 8/6/2024 | Before |
| 8/6/2024 | TOR | Brown,H | Demoted to reserve roster | | | Before |
| 8/6/2024 | TOR | Hendricks | Promoted to active roster | | | Before |
| 8/9/2024 | CUY | Flaherty | Demoted to reserve roster | | | Before |
| 8/9/2024 | CUY | Garrett,B | Activated from Injured List | | | Before |
| 8/9/2024 | DSP | Boyle | Placed on Injured List | | 8/9/2024 | Before |
| 8/9/2024 | DSP | German | Demoted to reserve roster | | | Before |
| 8/9/2024 | DSP | Kopech | Promoted to active roster | | | Before |
| 8/9/2024 | DSP | Lynn | Promoted to active roster | | | Before |
| 8/9/2024 | DSP | May,D | Demoted to reserve roster | | | Before |
| 8/9/2024 | DSP | Rea | Promoted to active roster | | | Before |
| 8/9/2024 | PUE | Schwarber | Promoted to active roster | | | Before |
| 8/9/2024 | PUE | Young,JS | Demoted to reserve roster | | | Before |
| 8/12/2024 | CGS | Medina | Demoted to reserve roster | | | Before |
| 8/12/2024 | CGS | Sale | Activated from Injured List | | | Before |
| 8/12/2024 | CLE | Carter | Demoted to reserve roster | | | Before |
| 8/12/2024 | CLE | Encarnacn-Stran | Promoted to active roster | | | Before |
| 8/12/2024 | NHP | Hurt | Demoted to reserve roster | | | Before |
| 8/12/2024 | NHP | Verlander | Activated from Injured List | | | Before |
| 8/15/2024 | CAP | Dominguez,J | Demoted to reserve roster | | | Before |
| 8/15/2024 | CAP | Pasquantino | Demoted to reserve roster | | | Before |
| 8/15/2024 | CAP | Peraza | Promoted to active roster | | | Before |
| 8/15/2024 | CAP | Rafaela | Promoted to active roster | | | Before |
| 8/15/2024 | CED | Arenado | Activated from Injured List | | | Before |
| 8/15/2024 | CED | Smith,K | Demoted to reserve roster | | | Before |
| 8/15/2024 | CUY | Fletcher,Do | Demoted to reserve roster | | | Before |
| 8/15/2024 | CUY | Funderburk | Promoted to active roster | | | Before |
| 8/15/2024 | CUY | Marte,N | Demoted to reserve roster | | | Before |
| 8/15/2024 | CUY | Miller,S | Demoted to reserve roster | | | Before |
| 8/15/2024 | CUY | Palencia | Promoted to active roster | | | Before |
| 8/15/2024 | CUY | Thomas,A | Promoted to active roster | | | Before |
| 8/15/2024 | DSP | German | Promoted to active roster | | | Before |
| 8/15/2024 | DSP | Lynn | Demoted to reserve roster | | | Before |
| 8/15/2024 | DSP | May,D | Promoted to active roster | | | Before |
| 8/15/2024 | DSP | Rea | Demoted to reserve roster | | | Before |
| 8/15/2024 | DUR | Kahnle | Demoted to reserve roster | | | Before |
| 8/15/2024 | DUR | Monasterio | Promoted to active roster | | | Before |
| 8/15/2024 | DUR | Musgrove | Activated from Injured List | | | Before |
| 8/15/2024 | DUR | Paddack | Demoted to reserve roster | | | Before |
| 8/15/2024 | DUR | Urshela | Demoted to reserve roster | | | Before |
| 8/15/2024 | DUR | Weissert | Promoted to active roster | | | Before |
| 8/18/2024 | CAP | Hampson | Demoted to reserve roster | | | Before |
| 8/18/2024 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 8/18/2024 | CAP | Murphy,S | Activated from Injured List | | | Before |
| 8/18/2024 | CAP | Story | Promoted to active roster | | | Before |
| 8/18/2024 | NHP | Alexander,T | Demoted to reserve roster | | | Before |
| 8/18/2024 | NHP | Hurt | Promoted to active roster | | | Before |
| 8/18/2024 | NHP | Megill,Tr | Demoted to reserve roster | | | Before |
| 8/18/2024 | NHP | Nelson,R | Activated from Injured List | | | Before |
| 8/21/2024 | CUY | Kirilloff | Activated from Injured List | | | Before |
| 8/21/2024 | CUY | Palencia | Demoted to reserve roster | | | Before |
| 8/21/2024 | PUE | Cabrera,G | Promoted to active roster | | | Before |
| 8/21/2024 | PUE | Lewis,R | Demoted to reserve roster | | | Before |
| 8/21/2024 | PUE | Saalfrank | Demoted to reserve roster | | | Before |
| 8/21/2024 | PUE | Wisdom | Promoted to active roster | | | Before |
| 8/21/2024 | WTB | Adell | Promoted to active roster | | | Before |
| 8/21/2024 | WTB | Rodgers | Demoted to reserve roster | | | Before |
| 8/21/2024 | WTB | Scherzer | Activated from Injured List | | | Before |
| 8/24/2024 | CED | De Los Santos,Y | Promoted to active roster | | | Before |
| 8/24/2024 | CED | Helsley | Demoted to reserve roster | | | Before |
| 8/24/2024 | CLE | Carter | Promoted to active roster | | | Before |
| 8/24/2024 | CLE | Moniak | Demoted to reserve roster | | | Before |
| 8/24/2024 | CLE | Moniak | Promoted to active roster | | | Before |
| 8/24/2024 | CLE | Raley,L | Demoted to reserve roster | | | Before |
| 8/24/2024 | CLE | Raley,L | Promoted to active roster | | | Before |
| 8/24/2024 | CLE | Siri | Demoted to reserve roster | | | Before |
| 8/24/2024 | DSP | German | Demoted to reserve roster | | | Before |
| 8/24/2024 | DSP | Lynn | Promoted to active roster | | | Before |
| 8/24/2024 | DSP | May,D | Demoted to reserve roster | | | Before |
| 8/24/2024 | DSP | Rea | Promoted to active roster | | | Before |
| 8/24/2024 | PUE | Robles | Activated from Injured List | | | Before |
| 8/24/2024 | PUE | Wisdom | Placed on Injured List | | 8/23/2024 | Before |
| 8/24/2024 | SPR | De La Cruz,B | Promoted to active roster | | | Before |
| 8/24/2024 | SPR | Grichuk | Placed on Injured List | | 8/22/2024 | Before |
| 8/24/2024 | TOR | Manning | Demoted to reserve roster | | | Before |
| 8/24/2024 | TOR | Pepiot | Promoted to active roster | | | Before |
| 8/27/2024 | DSP | Boyle | Activated from Injured List | | | Before |
| 8/27/2024 | DSP | German | Promoted to active roster | | | Before |
| 8/27/2024 | DSP | Kopech | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | Loaisiga | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | Lynn | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | May,D | Promoted to active roster | | | Before |
| 8/27/2024 | DSP | Oviedo | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | Oviedo | Promoted to active roster | | | Before |
| 8/27/2024 | DSP | Peterson,J | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | Schoop | Demoted to reserve roster | | | Before |
| 8/27/2024 | DSP | Schoop | Promoted to active roster | | | Before |
| 8/27/2024 | DSP | Urias,L | Activated from Injured List | | | Before |
| 8/27/2024 | NDF | Altuve | Demoted to reserve roster | | | Before |
| 8/27/2024 | NDF | Garcia,LH | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Garcia,Ro | Demoted to reserve roster | | | Before |
| 8/27/2024 | NDF | Garcia,Ro | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Gonzalez,V | Demoted to reserve roster | | | Before |
| 8/27/2024 | NDF | Jackson,L | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Kelly,Mi | Demoted to reserve roster | | | Before |
| 8/27/2024 | NDF | Kelly,Mi | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Lopez,Jac | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Rendon | Promoted to active roster | | | Before |
| 8/27/2024 | NDF | Stewart,DJ | Demoted to reserve roster | | | Before |
| 8/27/2024 | NDF | Strahm | Demoted to reserve roster | | | Before |
| 8/27/2024 | NHP | Hurt | Demoted to reserve roster | | | Before |
| 8/27/2024 | NHP | Robertson,N | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Brown,H | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Carpenter,M | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Clement | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Crawford,K | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Greene,H | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Hendricks | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Higashioka | Promoted to active roster | | | Before |
| 8/27/2024 | TOR | Murphy,T | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Seager | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Suarez,Ro | Demoted to reserve roster | | | Before |
| 8/27/2024 | TOR | Whitlock | Promoted to active roster | | | Before |
| 8/30/2024 | CLE | Arroyo | Promoted to active roster | | | Before |
| 8/30/2024 | CLE | McLain | Demoted to reserve roster | | | Before |
| 8/30/2024 | CLE | Ohtani | Demoted to reserve roster | | | Before |
| 8/30/2024 | CLE | Siri | Promoted to active roster | | | Before |
| 8/30/2024 | NDF | Garcia,Ro | Promoted to active roster | | | Before |
| 8/30/2024 | NDF | Jackson,L | Demoted to reserve roster | | | Before |
| 8/30/2024 | NDF | Narvaez | Promoted to active roster | | | Before |
| 8/30/2024 | NDF | Rendon | Demoted to reserve roster | | | Before |
| 8/30/2024 | OLL | Ashcraft | Demoted to reserve roster | | | Before |
| 8/30/2024 | OLL | deGrom | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Albies | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Arenado | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Barrero | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Barria | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Bautista | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Corbin | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Diaz,Yai | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Doyle,B | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Freeland | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Gallen | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Kelly,K | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Kiermaier | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Kirby | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | McArthur | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Miller,Bo | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Nola,Aa | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Palacios,R | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Smith,K | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Staumont | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Thompson,ZD | Promoted to active roster | | | Before |
| 9/2/2024 | CED | Tovar | Demoted to reserve roster | | | Before |
| 9/2/2024 | CED | Wallach | Promoted to active roster | | | Before |
| 9/2/2024 | HOL | Donovan | Demoted to reserve roster | | | Before |
| 9/2/2024 | HOL | Gallo | Promoted to active roster | | | Before |
| 9/2/2024 | NDF | Mullins | Placed on Injured List | | 8/14/2024 | Before |
| 9/2/2024 | NDF | Rendon | Promoted to active roster | | | Before |
| 9/2/2024 | NHP | Carlson | Demoted to reserve roster | | | Before |
| 9/2/2024 | NHP | Rosario,A | Promoted to active roster | | | Before |
| 9/2/2024 | WTB | Castro,MI | Promoted to active roster | | | Before |
| 9/2/2024 | WTB | Chavez | Demoted to reserve roster | | | Before |
| 9/5/2024 | CUY | Arias | Demoted to reserve roster | | | Before |
| 9/5/2024 | CUY | Armstrong | Demoted to reserve roster | | | Before |
| 9/5/2024 | CUY | Flaherty | Promoted to active roster | | | Before |
| 9/5/2024 | CUY | Garrett,B | Placed on Injured List | | 9/5/2024 | Before |
| 9/5/2024 | CUY | Loftin | Demoted to reserve roster | | | Before |
| 9/5/2024 | CUY | Miller,S | Promoted to active roster | | | Before |
| 9/5/2024 | CUY | Palencia | Promoted to active roster | | | Before |
| 9/5/2024 | CUY | Walls | Promoted to active roster | | | Before |
| 9/5/2024 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 9/5/2024 | DSP | Kopech | Promoted to active roster | | | Before |
| 9/5/2024 | DSP | Lynn | Promoted to active roster | | | Before |
| 9/5/2024 | DSP | May,D | Demoted to reserve roster | | | Before |
| 9/5/2024 | DUR | Devenski | Demoted to reserve roster | | | Before |
| 9/5/2024 | DUR | Wesneski | Promoted to active roster | | | Before |
| 9/8/2024 | AUR | Batten | Demoted to reserve roster | | | Before |
| 9/8/2024 | AUR | Curry | Activated from Injured List | | | Before |
| 9/8/2024 | AUR | Erceg | Promoted to active roster | | | Before |
| 9/8/2024 | AUR | Miller,M | Demoted to reserve roster | | | Before |
| 9/8/2024 | CGS | Civale | Demoted to reserve roster | | | Before |
| 9/8/2024 | CGS | Karinchak | Demoted to reserve roster | | | Before |
| 9/8/2024 | CGS | Liberatore | Promoted to active roster | | | Before |
| 9/8/2024 | CGS | Medina | Promoted to active roster | | | Before |
| 9/8/2024 | CLE | Encarnacn-Stran | Demoted to reserve roster | | | Before |
| 9/8/2024 | CLE | Ohtani | Promoted to active roster | | | Before |
| 9/8/2024 | DSP | Azocar | Promoted to active roster | | | Before |
| 9/8/2024 | DSP | Boyle | Promoted to active roster | | | Before |
| 9/8/2024 | DSP | Littell | Demoted to reserve roster | | | Before |
| 9/8/2024 | DSP | Suwinski | Placed on Injured List | | 9/6/2024 | Before |
| 9/8/2024 | DUR | Aranda | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Arozarena | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Basabe | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Bradford | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Brennan | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Chisholm | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Conforto | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Drury | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Freeman,T | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Kershaw | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Lyles | Activated from Injured List | | | Before |
| 9/8/2024 | DUR | Martinez,JD | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | McCann | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Mitchell,G | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Musgrove | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Ortiz,J | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Outman | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Polanco | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Pratto | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Richardson | Promoted to active roster | | | Before |
| 9/8/2024 | DUR | Rodriguez,Ed | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Senzel | Demoted to reserve roster | | | Before |
| 9/8/2024 | DUR | Stephenson,T | Demoted to reserve roster | | | Before |
| 9/8/2024 | HOL | Alcantara | Demoted to reserve roster | | | Before |
| 9/8/2024 | HOL | Means | Promoted to active roster | | | Before |
| 9/8/2024 | OLL | Blackburn | Placed on Injured List | | 9/6/2024 | Before |
| 9/8/2024 | OLL | Gorman | Placed on Injured List | | 9/6/2024 | Before |
| 9/8/2024 | OLL | Miranda | Promoted to active roster | | | Before |
| 9/8/2024 | OLL | Weathers | Promoted to active roster | | | Before |
| 9/8/2024 | PRO | Glasnow | Placed on Injured List | | 9/8/2024 | Before |
| 9/8/2024 | PRO | Mahle | Activated from Injured List | | | Before |
| 9/8/2024 | SPR | De La Cruz,B | Demoted to reserve roster | | | Before |
| 9/8/2024 | SPR | Grichuk | Activated from Injured List | | | Before |
| 9/11/2024 | AUR | Curry | Placed on Injured List | | 9/9/2024 | Before |
| 9/11/2024 | AUR | Jansen,D | Placed on Injured List | | 9/9/2024 | Before |
| 9/11/2024 | AUR | Kelly,C | Promoted to active roster | | | Before |
| 9/11/2024 | AUR | Matz | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Bradley,T | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Butler | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Eflin | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Encarnacn-Stran | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Hayes | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Kjerstad | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Lodolo | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Nootbaar | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Ohtani | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Rocchio | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Senga | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Siri | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Stroman | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Stroman | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Stroman | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | Stroman | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | White,O | Demoted to reserve roster | | | Before |
| 9/11/2024 | CLE | White,O | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | White,O | Promoted to active roster | | | Before |
| 9/11/2024 | CLE | Woodruff | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Acuna | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Arias | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Bogaerts | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Casas | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Fletcher,Do | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | France,T | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Gelof | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Kirilloff | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Loftin | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Marte,N | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Mateo | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Miller,S | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Nimmo | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Pereira | Promoted to active roster | | | Before |
| 9/11/2024 | CUY | Raleigh | Demoted to reserve roster | | | Before |
| 9/11/2024 | CUY | Woods Richardso | Promoted to active roster | | | Before |
| 9/11/2024 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 9/11/2024 | DSP | Cimber | Promoted to active roster | | | Before |
| 9/11/2024 | NHP | Luciano | Promoted to active roster | | | Before |
| 9/11/2024 | NHP | Luplow | Promoted to active roster | | | Before |
| 9/11/2024 | NHP | Munoz | Demoted to reserve roster | | | Before |
| 9/11/2024 | NHP | Stewart,B | Demoted to reserve roster | | | Before |
| 9/11/2024 | PRO | O'Hoppe | Placed on Injured List | | 9/9/2024 | Before |
| 9/11/2024 | PRO | Wells,A | Promoted to active roster | | | Before |
| 9/11/2024 | PUE | Bieber | Demoted to reserve roster | | | Before |
| 9/11/2024 | PUE | Hancock | Promoted to active roster | | | Before |