| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/5/2023 | RMH | Alvarez,F | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Boyd | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Bradish | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Castro,R | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Castro,W | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Chavis | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Contreras,R | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Cooper | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Davis,JD | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | De Jong | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Dunn | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Eaton | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Gonzales | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Gore,M | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Haggerty | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Herget,J | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Isbel | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Jimenez,J | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Kelly,C | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Kowar | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Kremer | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Lee,D | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Liberatore | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Martin,D | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Martinez,S | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Meneses | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Mercedes | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Mize | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Moll | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Montero,E | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Moore,D | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Ortiz,LF | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Perdomo,G | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Perez,Ci | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Refsnyder | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Robert | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Sewald | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Steele | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Suarez,E | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Thompson,B | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Trammell | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Vientos | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Wells,T | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Wendle | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Wilson,B | Acquired via trade | SEA | | After |
| 4/5/2023 | RMH | Yepez | Acquired via trade | SEA | | After |
| 4/5/2023 | SEA | Alvarez,F | Traded away | RMH | | After |
| 4/5/2023 | SEA | Boyd | Traded away | RMH | | After |
| 4/5/2023 | SEA | Bradish | Traded away | RMH | | After |
| 4/5/2023 | SEA | Castro,R | Traded away | RMH | | After |
| 4/5/2023 | SEA | Castro,W | Traded away | RMH | | After |
| 4/5/2023 | SEA | Chavis | Traded away | RMH | | After |
| 4/5/2023 | SEA | Contreras,R | Traded away | RMH | | After |
| 4/5/2023 | SEA | Cooper | Traded away | RMH | | After |
| 4/5/2023 | SEA | Davis,JD | Traded away | RMH | | After |
| 4/5/2023 | SEA | De Jong | Traded away | RMH | | After |
| 4/5/2023 | SEA | Dunn | Traded away | RMH | | After |
| 4/5/2023 | SEA | Eaton | Traded away | RMH | | After |
| 4/5/2023 | SEA | Gonzales | Traded away | RMH | | After |
| 4/5/2023 | SEA | Gore,M | Traded away | RMH | | After |
| 4/5/2023 | SEA | Haggerty | Traded away | RMH | | After |
| 4/5/2023 | SEA | Herget,J | Traded away | RMH | | After |
| 4/5/2023 | SEA | Isbel | Traded away | RMH | | After |
| 4/5/2023 | SEA | Jimenez,J | Traded away | RMH | | After |
| 4/5/2023 | SEA | Kelly,C | Traded away | RMH | | After |
| 4/5/2023 | SEA | Kowar | Traded away | RMH | | After |
| 4/5/2023 | SEA | Kremer | Traded away | RMH | | After |
| 4/5/2023 | SEA | Lee,D | Traded away | RMH | | After |
| 4/5/2023 | SEA | Liberatore | Traded away | RMH | | After |
| 4/5/2023 | SEA | Martin,D | Traded away | RMH | | After |
| 4/5/2023 | SEA | Martinez,S | Traded away | RMH | | After |
| 4/5/2023 | SEA | Meneses | Traded away | RMH | | After |
| 4/5/2023 | SEA | Mercedes | Traded away | RMH | | After |
| 4/5/2023 | SEA | Mize | Traded away | RMH | | After |
| 4/5/2023 | SEA | Moll | Traded away | RMH | | After |
| 4/5/2023 | SEA | Montero,E | Traded away | RMH | | After |
| 4/5/2023 | SEA | Moore,D | Traded away | RMH | | After |
| 4/5/2023 | SEA | Ortiz,LF | Traded away | RMH | | After |
| 4/5/2023 | SEA | Perdomo,G | Traded away | RMH | | After |
| 4/5/2023 | SEA | Perez,Ci | Traded away | RMH | | After |
| 4/5/2023 | SEA | Refsnyder | Traded away | RMH | | After |
| 4/5/2023 | SEA | Robert | Traded away | RMH | | After |
| 4/5/2023 | SEA | Sewald | Traded away | RMH | | After |
| 4/5/2023 | SEA | Steele | Traded away | RMH | | After |
| 4/5/2023 | SEA | Suarez,E | Traded away | RMH | | After |
| 4/5/2023 | SEA | Thompson,B | Traded away | RMH | | After |
| 4/5/2023 | SEA | Trammell | Traded away | RMH | | After |
| 4/5/2023 | SEA | Vientos | Traded away | RMH | | After |
| 4/5/2023 | SEA | Wells,T | Traded away | RMH | | After |
| 4/5/2023 | SEA | Wendle | Traded away | RMH | | After |
| 4/5/2023 | SEA | Wilson,B | Traded away | RMH | | After |
| 4/5/2023 | SEA | Yepez | Traded away | RMH | | After |
| 4/8/2023 | CUY | Patino | Demoted to reserve roster | | | Before |
| 4/8/2023 | CUY | Woods Richardso | Demoted to reserve roster | | | Before |
| 4/11/2023 | CAP | Bummer | Promoted to active roster | | | Before |
| 4/11/2023 | CAP | Foley | Placed on Injured List | | 4/10/2023 | Before |
| 4/11/2023 | DSP | Hudson,Dan | Demoted to reserve roster | | | Before |
| 4/11/2023 | DSP | Rogers,Ty | Promoted to active roster | | | Before |
| 4/11/2023 | DUR | Marinaccio | Placed on Injured List | | 4/11/2023 | Before |
| 4/11/2023 | DUR | Rojas,M | Promoted to active roster | | | Before |
| 4/17/2023 | PRO | Bryant | Placed on Injured List | | 4/13/2023 | Before |
| 4/17/2023 | PRO | Dalbec | Promoted to active roster | | | Before |
| 4/20/2023 | wtb | Keller,M | Promoted to active roster | | | Before |
| 4/20/2023 | wtb | Means | Demoted to reserve roster | | | Before |
| 4/23/2023 | CAL | Baz | Promoted to active roster | | | Before |
| 4/23/2023 | CAL | Crawford,K | Placed on Injured List | | 4/23/2023 | Before |
| 4/23/2023 | DSP | Castro,H | Promoted to active roster | | | Before |
| 4/23/2023 | DSP | Pena | Placed on Injured List | | 4/21/2023 | Before |
| 4/23/2023 | HOL | Doval | Promoted to active roster | | | Before |
| 4/23/2023 | HOL | Graterol | Demoted to reserve roster | | | Before |
| 4/23/2023 | OLL | Alzolay | Promoted to active roster | | | Before |
| 4/23/2023 | OLL | Hand | Placed on Injured List | | 4/23/2023 | Before |
| 4/23/2023 | OLL | Junis | Placed on Injured List | | 4/23/2023 | Before |
| 4/23/2023 | OLL | Megill,Ty | Promoted to active roster | | | Before |
| 4/23/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 4/23/2023 | TOR | Carpenter,M | Demoted to reserve roster | | | Before |
| 4/23/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 4/23/2023 | TOR | Haniger | Promoted to active roster | | | Before |
| 4/23/2023 | TOR | Manning | Demoted to reserve roster | | | Before |
| 4/23/2023 | TOR | Winker | Promoted to active roster | | | Before |
| 4/26/2023 | AUR | Morris | Promoted to active roster | | | Before |
| 4/26/2023 | AUR | Narvaez | Promoted to active roster | | | Before |
| 4/26/2023 | AUR | Torrens | Placed on Injured List | | 4/25/2023 | Before |
| 4/26/2023 | AUR | Wright | Demoted to reserve roster | | | Before |
| 4/26/2023 | CAP | Bummer | Demoted to reserve roster | | | Before |
| 4/26/2023 | CAP | Foley | Activated from Injured List | | | Before |
| 4/26/2023 | CAP | Manaea | Promoted to active roster | | | Before |
| 4/26/2023 | CAP | Wood | Placed on Injured List | | 4/24/2023 | Before |
| 4/26/2023 | CED | Albies | Placed on Injured List | | 4/23/2023 | Before |
| 4/26/2023 | CED | Brosseau | Promoted to active roster | | | Before |
| 4/26/2023 | CED | Smith,K | Promoted to active roster | | | Before |
| 4/26/2023 | CED | Solano | Placed on Injured List | | 4/25/2023 | Before |
| 4/26/2023 | CLE | Alfaro | Placed on Injured List | | 4/18/2023 | Before |
| 4/26/2023 | CLE | Higgins | Placed on Injured List | | 4/21/2023 | Before |
| 4/26/2023 | CLE | Raley,L | Promoted to active roster | | | Before |
| 4/26/2023 | CLE | Walsh,Jar | Promoted to active roster | | | Before |
| 4/26/2023 | DSP | Hendricks | Demoted to reserve roster | | | Before |
| 4/26/2023 | PEA | Stroman | Placed on Injured List | | 4/26/2023 | Before |
| 4/26/2023 | PEA | White,M | Promoted to active roster | | | Before |
| 4/26/2023 | PRO | Dalbec | Placed on Injured List | | 4/24/2023 | Before |
| 4/26/2023 | PRO | Fairchild | Promoted to active roster | | | Before |
| 4/26/2023 | TOR | Alvarez,Y | Placed on Injured List | | 4/25/2023 | Before |
| 4/26/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 4/26/2023 | TOR | Manning | Promoted to active roster | | | Before |
| 4/26/2023 | TOR | Ruf | Promoted to active roster | | | Before |
| 4/28/2023 | CLE | Flaherty | Traded away | CUY | | After |
| 4/28/2023 | CLE | Hummel | Acquired via trade | CUY | | After |
| 4/28/2023 | CLE | Murfee | Acquired via trade | CUY | | After |
| 4/28/2023 | CLE | Neris | Acquired via trade | CUY | | After |
| 4/28/2023 | CLE | Wisler | Acquired via trade | CUY | | After |
| 4/28/2023 | CUY | Flaherty | Acquired via trade | CLE | | After |
| 4/28/2023 | CUY | Hummel | Traded away | CLE | | After |
| 4/28/2023 | CUY | Murfee | Traded away | CLE | | After |
| 4/28/2023 | CUY | Neris | Traded away | CLE | | After |
| 4/28/2023 | CUY | Wisler | Traded away | CLE | | After |
| 4/29/2023 | CED | Brash | Promoted to active roster | | | Before |
| 4/29/2023 | CED | Thompson,K | Placed on Injured List | | 4/29/2023 | Before |
| 4/29/2023 | CLE | Garcia,Ro | Demoted to reserve roster | | | Before |
| 4/29/2023 | CLE | Hummel | Promoted to active roster | | | Before |
| 4/29/2023 | CLE | Lambert | Demoted to reserve roster | | | Before |
| 4/29/2023 | CLE | Raley,L | Demoted to reserve roster | | | Before |
| 4/29/2023 | CUY | Heasley | Promoted to active roster | | | Before |
| 4/29/2023 | CUY | Thompson,M | Promoted to active roster | | | Before |
| 4/29/2023 | CUY | Trejo | Demoted to reserve roster | | | Before |
| 4/29/2023 | CUY | Walls | Promoted to active roster | | | Before |
| 5/2/2023 | DSP | Hudson,Dan | Promoted to active roster | | | Before |
| 5/2/2023 | DUR | Gordon | Placed on Injured List | | 4/30/2023 | Before |
| 5/2/2023 | DUR | Hill,G | Placed on Injured List | | 4/30/2023 | Before |
| 5/2/2023 | DUR | Marinaccio | Activated from Injured List | | | Before |
| 5/2/2023 | DUR | Paddack | Promoted to active roster | | | Before |
| 5/5/2023 | DSP | Pena | Activated from Injured List | | | Before |
| 5/5/2023 | DSP | Rogers,Ty | Demoted to reserve roster | | | Before |
| 5/5/2023 | OLL | Alzolay | Demoted to reserve roster | | | Before |
| 5/5/2023 | OLL | Barlow,J | Promoted to active roster | | | Before |
| 5/5/2023 | OLL | Greinke | Placed on Injured List | | 5/5/2023 | Before |
| 5/5/2023 | OLL | Smeltzer | Promoted to active roster | | | Before |
| 5/5/2023 | wtb | Bickford | Promoted to active roster | | | Before |
| 5/5/2023 | wtb | Cortes | Placed on Injured List | | 5/2/2023 | Before |
| 5/8/2023 | DUR | Ahmed | Promoted to active roster | | | Before |
| 5/8/2023 | DUR | Wong,K | Placed on Injured List | | 5/3/2023 | Before |
| 5/8/2023 | PUE | Hernandez,T | Placed on Injured List | | 5/6/2023 | Before |
| 5/8/2023 | PUE | Herrera,O | Promoted to active roster | | | Before |
| 5/11/2023 | CED | Brash | Demoted to reserve roster | | | Before |
| 5/11/2023 | CED | Thompson,K | Activated from Injured List | | | Before |
| 5/11/2023 | CHI | La Stella | Placed on Injured List | | 4/24/2023 | Before |
| 5/11/2023 | CHI | Ozuna | Promoted to active roster | | | Before |
| 5/11/2023 | CLE | Garcia,Ro | Promoted to active roster | | | Before |
| 5/11/2023 | CLE | Lodolo | Placed on Injured List | | 5/11/2023 | Before |
| 5/11/2023 | OLL | Bote | Promoted to active roster | | | Before |
| 5/11/2023 | OLL | Junis | Activated from Injured List | | | Before |
| 5/11/2023 | OLL | Smeltzer | Demoted to reserve roster | | | Before |
| 5/11/2023 | OLL | Ward | Placed on Injured List | | 5/10/2023 | Before |
| 5/11/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 5/11/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 5/11/2023 | TOR | Manning | Demoted to reserve roster | | | Before |
| 5/11/2023 | TOR | Mayza | Promoted to active roster | | | Before |
| 5/14/2023 | PRO | Bryant | Activated from Injured List | | | Before |
| 5/14/2023 | PRO | Fairchild | Demoted to reserve roster | | | Before |
| 5/14/2023 | TOR | Alvarez,Y | Activated from Injured List | | | Before |
| 5/14/2023 | TOR | Ruf | Demoted to reserve roster | | | Before |
| 5/17/2023 | CAP | Manaea | Demoted to reserve roster | | | Before |
| 5/17/2023 | CAP | Wood | Activated from Injured List | | | Before |
| 5/17/2023 | CED | Almora | Promoted to active roster | | | Before |
| 5/17/2023 | CED | Brash | Promoted to active roster | | | Before |
| 5/17/2023 | CED | Freeland | Placed on Injured List | | 5/16/2023 | Before |
| 5/17/2023 | CED | Kiermaier | Placed on Injured List | | 5/15/2023 | Before |
| 5/17/2023 | DUR | Chisholm | Placed on Injured List | | 5/12/2023 | Before |
| 5/17/2023 | DUR | Hill,G | Activated from Injured List | | | Before |
| 5/17/2023 | DUR | Paddack | Demoted to reserve roster | | | Before |
| 5/17/2023 | DUR | Senzel | Promoted to active roster | | | Before |
| 5/17/2023 | PUE | Iglesias,J | Placed on Injured List | | 5/14/2023 | Before |
| 5/17/2023 | PUE | Lewis,R | Promoted to active roster | | | Before |
| 5/17/2023 | PUE | Marquez | Placed on Injured List | | 5/15/2023 | Before |
| 5/17/2023 | PUE | Overton | Promoted to active roster | | | Before |
| 5/17/2023 | wtb | Barnes,A | Placed on Injured List | | 5/16/2023 | Before |
| 5/17/2023 | wtb | Romine | Promoted to active roster | | | Before |
| 5/20/2023 | AUR | Bouchard | Demoted to reserve roster | | | Before |
| 5/20/2023 | AUR | Call | Promoted to active roster | | | Before |
| 5/20/2023 | AUR | Fortes | Promoted to active roster | | | Before |
| 5/20/2023 | AUR | Jansen,D | Demoted to reserve roster | | | Before |
| 5/20/2023 | AUR | Mathias | Demoted to reserve roster | | | Before |
| 5/20/2023 | AUR | Maton,N | Promoted to active roster | | | Before |
| 5/20/2023 | AUR | Morris | Demoted to reserve roster | | | Before |
| 5/20/2023 | AUR | Torrens | Activated from Injured List | | | Before |
| 5/20/2023 | AUR | Torrens | Demoted to reserve roster | | | Before |
| 5/20/2023 | AUR | Wright | Promoted to active roster | | | Before |
| 5/20/2023 | CLE | Higgins | Activated from Injured List | | | Before |
| 5/20/2023 | CLE | Walsh,Jar | Demoted to reserve roster | | | Before |
| 5/20/2023 | OLL | Bote | Demoted to reserve roster | | | Before |
| 5/20/2023 | OLL | Hand | Activated from Injured List | | | Before |
| 5/20/2023 | OLL | Jansen,K | Placed on Injured List | | 5/19/2023 | Before |
| 5/20/2023 | OLL | Ward | Activated from Injured List | | | Before |
| 5/20/2023 | SPR | Clarke | Placed on Injured List | | 5/19/2023 | Before |
| 5/20/2023 | SPR | Smith,WM | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 5/20/2023 | TOR | Casali | Demoted to reserve roster | | | Before |
| 5/20/2023 | TOR | Higashioka | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | Kelly,J | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | Manning | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | Mayza | Demoted to reserve roster | | | Before |
| 5/20/2023 | TOR | Milner | Promoted to active roster | | | Before |
| 5/20/2023 | TOR | Stephan | Demoted to reserve roster | | | Before |
| 5/20/2023 | TOR | Whitlock | Demoted to reserve roster | | | Before |
| 5/23/2023 | CAL | Andujar | Promoted to active roster | | | Before |
| 5/23/2023 | CAL | Baz | Demoted to reserve roster | | | Before |
| 5/23/2023 | CAL | Belt | Placed on Injured List | | 5/19/2023 | Before |
| 5/23/2023 | CAL | Crawford,K | Activated from Injured List | | | Before |
| 5/23/2023 | CAL | Ruiz,E | Promoted to active roster | | | Before |
| 5/23/2023 | CAL | Votto | Placed on Injured List | | 5/23/2023 | Before |
| 5/23/2023 | CLE | Alfaro | Activated from Injured List | | | Before |
| 5/23/2023 | CLE | Hummel | Demoted to reserve roster | | | Before |
| 5/23/2023 | DUR | Ahmed | Demoted to reserve roster | | | Before |
| 5/23/2023 | DUR | Gordon | Activated from Injured List | | | Before |
| 5/23/2023 | DUR | Senzel | Demoted to reserve roster | | | Before |
| 5/23/2023 | DUR | Wong,K | Activated from Injured List | | | Before |
| 5/23/2023 | HOL | Graterol | Promoted to active roster | | | Before |
| 5/23/2023 | HOL | Kopech | Placed on Injured List | | 5/22/2023 | Before |
| 5/26/2023 | CAP | Donaldson | Placed on Injured List | | 5/26/2023 | Before |
| 5/26/2023 | CAP | Peraza | Promoted to active roster | | | Before |
| 5/26/2023 | CED | Albies | Activated from Injured List | | | Before |
| 5/26/2023 | CED | Almora | Placed on Injured List | | 5/26/2023 | Before |
| 5/26/2023 | DSP | Anderson,C | Promoted to active roster | | | Before |
| 5/26/2023 | DSP | German,D | Demoted to reserve roster | | | Before |
| 5/26/2023 | DSP | Hudson,Dan | Demoted to reserve roster | | | Before |
| 5/26/2023 | DSP | Rogers,Ty | Promoted to active roster | | | Before |
| 5/26/2023 | HOL | Graterol | Demoted to reserve roster | | | Before |
| 5/26/2023 | HOL | Lugo | Promoted to active roster | | | Before |
| 5/26/2023 | OLL | Greinke | Activated from Injured List | | | Before |
| 5/26/2023 | OLL | Loup | Demoted to reserve roster | | | Before |
| 5/26/2023 | PUE | Biggio | Demoted to reserve roster | | | Before |
| 5/26/2023 | PUE | Bush | Demoted to reserve roster | | | Before |
| 5/26/2023 | PUE | Cisnero | Promoted to active roster | | | Before |
| 5/26/2023 | PUE | Hernandez,T | Activated from Injured List | | | Before |
| 5/26/2023 | PUE | Iglesias,J | Activated from Injured List | | | Before |
| 5/26/2023 | PUE | Lewis,R | Demoted to reserve roster | | | Before |
| 5/26/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 5/26/2023 | TOR | Effross | Demoted to reserve roster | | | Before |
| 5/26/2023 | TOR | Manning | Demoted to reserve roster | | | Before |
| 5/26/2023 | TOR | Manoah | Placed on Injured List | | 5/24/2023 | Before |
| 5/26/2023 | TOR | Mayza | Promoted to active roster | | | Before |
| 5/26/2023 | TOR | Stephan | Promoted to active roster | | | Before |
| 5/29/2023 | PEA | Pepiot | Demoted to reserve roster | | | Before |
| 5/29/2023 | PEA | Stroman | Activated from Injured List | | | Before |
| 5/29/2023 | RMH | Contreras,R | Demoted to reserve roster | | | Before |
| 5/29/2023 | RMH | Davis,JD | Promoted to active roster | | | Before |
| 5/29/2023 | RMH | Gore,M | Promoted to active roster | | | Before |
| 5/29/2023 | RMH | Meneses | Demoted to reserve roster | | | Before |
| 5/29/2023 | RMH | Thompson,B | Promoted to active roster | | | Before |
| 5/29/2023 | RMH | Trammell | Demoted to reserve roster | | | Before |
| 5/29/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 5/29/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 5/29/2023 | TOR | Effross | Promoted to active roster | | | Before |
| 5/29/2023 | TOR | Kelly,J | Demoted to reserve roster | | | Before |
| 5/29/2023 | TOR | Manning | Promoted to active roster | | | Before |
| 5/29/2023 | TOR | Mayza | Demoted to reserve roster | | | Before |
| 5/29/2023 | TOR | Mayza | Promoted to active roster | | | Before |
| 5/29/2023 | TOR | Milner | Demoted to reserve roster | | | Before |
| 5/29/2023 | TOR | Whitlock | Promoted to active roster | | | Before |
| 5/29/2023 | TOR | Winker | Demoted to reserve roster | | | Before |
| 5/29/2023 | wtb | Bickford | Demoted to reserve roster | | | Before |
| 5/29/2023 | wtb | Cortes | Activated from Injured List | | | Before |
| 6/1/2023 | AUR | Kikuchi | Promoted to active roster | | | Before |
| 6/1/2023 | AUR | Wright | Placed on Injured List | | 5/31/2023 | Before |
| 6/1/2023 | CAP | Jameson | Promoted to active roster | | | Before |
| 6/1/2023 | CAP | McCullers | Demoted to reserve roster | | | Before |
| 6/1/2023 | OLL | Alberto | Promoted to active roster | | | Before |
| 6/1/2023 | OLL | Dickerson,C | Placed on Injured List | | 5/31/2023 | Before |
| 6/1/2023 | OLL | Hand | Demoted to reserve roster | | | Before |
| 6/1/2023 | OLL | Jansen,K | Activated from Injured List | | | Before |
| 6/1/2023 | PUE | Lopez,R | Placed on Injured List | | 5/30/2023 | Before |
| 6/1/2023 | PUE | Weissert | Promoted to active roster | | | Before |
| 6/1/2023 | SPR | Clarke | Activated from Injured List | | | Before |
| 6/1/2023 | SPR | Houser | Placed on Injured List | | 5/29/2023 | Before |
| 6/1/2023 | SPR | Smith,WM | Demoted to reserve roster | | | Before |
| 6/1/2023 | SPR | Thompson,Zach | Promoted to active roster | | | Before |
| 6/4/2023 | CAP | Bummer | Promoted to active roster | | | Before |
| 6/4/2023 | CAP | Matz | Demoted to reserve roster | | | Before |
| 6/4/2023 | CED | Brash | Demoted to reserve roster | | | Before |
| 6/4/2023 | CED | Brash | Promoted to active roster | | | Before |
| 6/4/2023 | CED | Brosseau | Demoted to reserve roster | | | Before |
| 6/4/2023 | CED | Kiermaier | Activated from Injured List | | | Before |
| 6/4/2023 | CED | Smith,K | Demoted to reserve roster | | | Before |
| 6/4/2023 | CED | Solano | Activated from Injured List | | | Before |
| 6/4/2023 | DSP | German,D | Promoted to active roster | | | Before |
| 6/4/2023 | DSP | Rogers,Ty | Demoted to reserve roster | | | Before |
| 6/7/2023 | CLE | Brieske | Placed on Injured List | | 5/30/2023 | Before |
| 6/7/2023 | CLE | Keller,B | Demoted to reserve roster | | | Before |
| 6/7/2023 | CLE | Lambert | Promoted to active roster | | | Before |
| 6/7/2023 | CLE | Lodolo | Activated from Injured List | | | Before |
| 6/7/2023 | DSP | Cordero | Demoted to reserve roster | | | Before |
| 6/7/2023 | DSP | Kreidler | Promoted to active roster | | | Before |
| 6/7/2023 | DSP | Solak | Demoted to reserve roster | | | Before |
| 6/7/2023 | DSP | Solak | Promoted to active roster | | | Before |
| 6/7/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 6/7/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 6/7/2023 | TOR | Cave | Promoted to active roster | | | Before |
| 6/7/2023 | TOR | Kelly,J | Promoted to active roster | | | Before |
| 6/7/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 6/7/2023 | TOR | Manning | Demoted to reserve roster | | | Before |
| 6/10/2023 | AUR | Kikuchi | Demoted to reserve roster | | | Before |
| 6/10/2023 | AUR | Wright | Activated from Injured List | | | Before |
| 6/10/2023 | CAP | Bummer | Demoted to reserve roster | | | Before |
| 6/10/2023 | CAP | Eovaldi | Demoted to reserve roster | | | Before |
| 6/10/2023 | CAP | Matz | Promoted to active roster | | | Before |
| 6/10/2023 | CAP | Meyers | Promoted to active roster | | | Before |
| 6/10/2023 | CAP | Pasquantino | Placed on Injured List | | 6/10/2023 | Before |
| 6/10/2023 | CED | Brash | Demoted to reserve roster | | | Before |
| 6/10/2023 | CED | Carpenter,K | Promoted to active roster | | | Before |
| 6/10/2023 | CED | Hall,Da | Demoted to reserve roster | | | Before |
| 6/10/2023 | CED | Lynch | Promoted to active roster | | | Before |
| 6/10/2023 | CUY | Heasley | Placed on Injured List | | 6/9/2023 | Before |
| 6/10/2023 | CUY | Woods Richardso | Promoted to active roster | | | Before |
| 6/13/2023 | CAP | Bummer | Promoted to active roster | | | Before |
| 6/13/2023 | CAP | Donaldson | Activated from Injured List | | | Before |
| 6/13/2023 | CAP | Eovaldi | Promoted to active roster | | | Before |
| 6/13/2023 | CAP | Matz | Demoted to reserve roster | | | Before |
| 6/13/2023 | CAP | Peraza | Demoted to reserve roster | | | Before |
| 6/13/2023 | OLL | Alberto | Demoted to reserve roster | | | Before |
| 6/13/2023 | OLL | Dickerson,C | Activated from Injured List | | | Before |
| 6/16/2023 | CAL | Andujar | Demoted to reserve roster | | | Before |
| 6/16/2023 | CAL | Belt | Activated from Injured List | | | Before |
| 6/16/2023 | CAL | Ruiz,E | Demoted to reserve roster | | | Before |
| 6/16/2023 | CAL | Votto | Activated from Injured List | | | Before |
| 6/16/2023 | DSP | Hudson,Dan | Promoted to active roster | | | Before |
| 6/16/2023 | DSP | Kreidler | Demoted to reserve roster | | | Before |
| 6/16/2023 | OLL | Smeltzer | Promoted to active roster | | | Before |
| 6/16/2023 | OLL | Verlander | Placed on Injured List | | 6/15/2023 | Before |
| 6/16/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | Brown,H | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Carpenter,M | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Casali | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Cave | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | Haniger | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | Higashioka | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | Kelly,J | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Luzardo | Demoted to reserve roster | | | Before |
| 6/16/2023 | TOR | Manning | Promoted to active roster | | | Before |
| 6/16/2023 | TOR | Manoah | Activated from Injured List | | | Before |
| 6/16/2023 | TOR | Mayza | Demoted to reserve roster | | | Before |
| 6/19/2023 | CAP | Manaea | Promoted to active roster | | | Before |
| 6/19/2023 | CAP | Rodriguez,Ed | Placed on Injured List | | 6/18/2023 | Before |
| 6/19/2023 | CUY | Patino | Promoted to active roster | | | Before |
| 6/19/2023 | CUY | Woods Richardso | Demoted to reserve roster | | | Before |
| 6/19/2023 | DSP | Delay | Promoted to active roster | | | Before |
| 6/19/2023 | DSP | German,D | Demoted to reserve roster | | | Before |
| 6/19/2023 | DSP | Matzek | Demoted to reserve roster | | | Before |
| 6/19/2023 | DSP | May,D | Promoted to active roster | | | Before |
| 6/19/2023 | HOL | Kopech | Activated from Injured List | | | Before |
| 6/19/2023 | HOL | Puk | Demoted to reserve roster | | | Before |
| 6/19/2023 | NHP | Nelson,R | Promoted to active roster | | | Before |
| 6/19/2023 | NHP | Springs | Placed on Injured List | | 6/19/2023 | Before |
| 6/19/2023 | SPR | Clarke | Demoted to reserve roster | | | Before |
| 6/19/2023 | SPR | Smith,WM | Promoted to active roster | | | Before |
| 6/22/2023 | DUR | Chisholm | Activated from Injured List | | | Before |
| 6/22/2023 | DUR | Wong,K | Placed on Injured List | | 6/10/2023 | Before |
| 6/22/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 6/22/2023 | TOR | Brown,H | Demoted to reserve roster | | | Before |
| 6/22/2023 | TOR | Carpenter,M | Demoted to reserve roster | | | Before |
| 6/22/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 6/22/2023 | TOR | Haniger | Promoted to active roster | | | Before |
| 6/22/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 6/22/2023 | TOR | Luzardo | Promoted to active roster | | | Before |
| 6/22/2023 | TOR | Manning | Demoted to reserve roster | | | Before |
| 6/22/2023 | TOR | Milner | Promoted to active roster | | | Before |
| 6/22/2023 | TOR | Winker | Promoted to active roster | | | Before |
| 6/25/2023 | CAP | Meyers | Demoted to reserve roster | | | Before |
| 6/25/2023 | CAP | Pasquantino | Activated from Injured List | | | Before |
| 6/25/2023 | CLE | Eflin | Demoted to reserve roster | | | Before |
| 6/25/2023 | CLE | Garcia,Ro | Demoted to reserve roster | | | Before |
| 6/25/2023 | CLE | Hicks,J | Promoted to active roster | | | Before |
| 6/25/2023 | CLE | Keller,B | Demoted to reserve roster | | | Before |
| 6/25/2023 | CLE | Keller,B | Promoted to active roster | | | Before |
| 6/25/2023 | CLE | Keller,B | Promoted to active roster | | | Before |
| 6/25/2023 | CLE | Lambert | Demoted to reserve roster | | | Before |
| 6/25/2023 | CLE | Oviedo | Promoted to active roster | | | Before |
| 6/25/2023 | PUE | Duran,Jh | Placed on Injured List | | 6/25/2023 | Before |
| 6/25/2023 | PUE | Lopez,R | Activated from Injured List | | | Before |
| 6/25/2023 | PUE | Marquez | Activated from Injured List | | | Before |
| 6/25/2023 | PUE | Overton | Demoted to reserve roster | | | Before |
| 6/27/2023 | DSP | Darvish | Traded away | HAV | | After |
| 6/27/2023 | DSP | Lopez,P | Acquired via trade | HAV | | After |
| 6/27/2023 | HAV | Darvish | Acquired via trade | DSP | | After |
| 6/27/2023 | HAV | Lopez,P | Traded away | DSP | | After |
| 6/28/2023 | PUE | Biggio | Promoted to active roster | | | Before |
| 6/28/2023 | PUE | Wisdom | Placed on Injured List | | 6/26/2023 | Before |
| 7/1/2023 | DUR | Duvall | Promoted to active roster | | | Before |
| 7/1/2023 | DUR | Mitchell,G | Promoted to active roster | | | Before |
| 7/1/2023 | DUR | Rojas,M | Demoted to reserve roster | | | Before |
| 7/1/2023 | DUR | Taveras | Demoted to reserve roster | | | Before |
| 7/1/2023 | DUR | Thompson,R | Demoted to reserve roster | | | Before |
| 7/1/2023 | DUR | Wong,K | Activated from Injured List | | | Before |
| 7/1/2023 | OLL | Junis | Placed on Injured List | | 6/29/2023 | Before |
| 7/1/2023 | OLL | Leiter | Promoted to active roster | | | Before |
| 7/4/2023 | CAP | Foley | Placed on Injured List | | 7/3/2023 | Before |
| 7/4/2023 | CAP | Hall,DL | Promoted to active roster | | | Before |
| 7/4/2023 | CAP | Jameson | Demoted to reserve roster | | | Before |
| 7/4/2023 | CAP | Manaea | Placed on Injured List | | 7/2/2023 | Before |
| 7/4/2023 | CAP | Matz | Promoted to active roster | | | Before |
| 7/4/2023 | CAP | Sale | Promoted to active roster | | | Before |
| 7/4/2023 | CUY | Garrett,S | Demoted to reserve roster | | | Before |
| 7/4/2023 | CUY | Heasley | Activated from Injured List | | | Before |
| 7/4/2023 | CUY | Leblanc | Demoted to reserve roster | | | Before |
| 7/4/2023 | CUY | Patino | Demoted to reserve roster | | | Before |
| 7/4/2023 | CUY | Soler | Promoted to active roster | | | Before |
| 7/4/2023 | CUY | Trejo | Promoted to active roster | | | Before |
| 7/4/2023 | NHP | Nelson,R | Demoted to reserve roster | | | Before |
| 7/4/2023 | NHP | Springs | Activated from Injured List | | | Before |
| 7/6/2023 | CAP | Adames | Acquired via trade | SPR | | After |
| 7/6/2023 | CAP | Donaldson | Traded away | SPR | | After |
| 7/6/2023 | SPR | Adames | Traded away | CAP | | After |
| 7/6/2023 | SPR | Donaldson | Acquired via trade | CAP | | After |
| 7/7/2023 | DSP | Pena | Placed on Injured List | | 7/7/2023 | Before |
| 7/7/2023 | DSP | Toro | Promoted to active roster | | | Before |
| 7/7/2023 | DUR | Finnegan | Promoted to active roster | | | Before |
| 7/7/2023 | DUR | Fried | Placed on Injured List | | 7/5/2023 | Before |
| 7/7/2023 | DUR | Gray,Jon | Placed on Injured List | | 7/6/2023 | Before |
| 7/7/2023 | DUR | Moran,J | Demoted to reserve roster | | | Before |
| 7/7/2023 | DUR | Paddack | Promoted to active roster | | | Before |
| 7/7/2023 | DUR | Wesneski | Promoted to active roster | | | Before |
| 7/7/2023 | OLL | Flexen | Placed on Injured List | | 7/5/2023 | Before |
| 7/7/2023 | OLL | Garcia,J | Promoted to active roster | | | Before |
| 7/9/2023 | CAP | Davies | Acquired via trade | DUR | | After |
| 7/9/2023 | CAP | Fletcher,D | Traded away | DUR | | After |
| 7/9/2023 | CAP | Hill,G | Acquired via trade | DUR | | After |
| 7/9/2023 | CAP | Lynn | Traded away | DUR | | After |
| 7/9/2023 | CAP | Waldichuk | Acquired via trade | DUR | | After |
| 7/9/2023 | DUR | Davies | Traded away | CAP | | After |
| 7/9/2023 | DUR | Fletcher,D | Acquired via trade | CAP | | After |
| 7/9/2023 | DUR | Hill,G | Traded away | CAP | | After |
| 7/9/2023 | DUR | Lynn | Acquired via trade | CAP | | After |
| 7/9/2023 | DUR | Waldichuk | Traded away | CAP | | After |
| 7/10/2023 | CED | Almora | Activated from Injured List | | | Before |
| 7/10/2023 | CED | Feyereisen | Promoted to active roster | | | Before |
| 7/10/2023 | CED | Gilbreath | Demoted to reserve roster | | | Before |
| 7/10/2023 | CED | Heineman | Promoted to active roster | | | Before |
| 7/10/2023 | CED | Kiermaier | Demoted to reserve roster | | | Before |
| 7/10/2023 | CED | Kinley | Promoted to active roster | | | Before |
| 7/10/2023 | CED | Langeliers | Demoted to reserve roster | | | Before |
| 7/10/2023 | CED | Thompson,Zack | Demoted to reserve roster | | | Before |
| 7/10/2023 | DUR | Fletcher,D | Demoted to reserve roster | | | Before |
| 7/10/2023 | DUR | Velasquez | Promoted to active roster | | | Before |
| 7/10/2023 | DUR | Wesneski | Demoted to reserve roster | | | Before |
| 7/10/2023 | DUR | Winder | Promoted to active roster | | | Before |
| 7/10/2023 | HAV | Machado,A | Signed | | | Before |
| 7/10/2023 | HAV | Machado,A | Demoted to reserve roster | | | Before |
| 7/10/2023 | NHP | Montas | Promoted to active roster | | | Before |
| 7/10/2023 | NHP | Morejon | Demoted to reserve roster | | | Before |
| 7/10/2023 | OLL | Alberto | Promoted to active roster | | | Before |
| 7/10/2023 | OLL | Garcia,J | Demoted to reserve roster | | | Before |
| 7/10/2023 | OLL | Verlander | Activated from Injured List | | | Before |
| 7/10/2023 | OLL | Ward | Placed on Injured List | | 7/9/2023 | Before |
| 7/10/2023 | PEA | Grossman | Placed on Injured List | | 7/7/2023 | Before |
| 7/10/2023 | PEA | Hernandez,Ya | Promoted to active roster | | | Before |
| 7/10/2023 | PEA | Snell | Placed on Injured List | | 7/6/2023 | Before |
| 7/10/2023 | PEA | Yarbrough | Promoted to active roster | | | Before |
| 7/10/2023 | PUE | Gonzalez,O | Demoted to reserve roster | | | Before |
| 7/10/2023 | PUE | Jones,N | Promoted to active roster | | | Before |
| 7/10/2023 | PUE | Pujols | Demoted to reserve roster | | | Before |
| 7/10/2023 | PUE | Vosler | Promoted to active roster | | | Before |
| 7/12/2023 | CAP | Bote | Acquired via trade | OLL | | After |
| 7/12/2023 | CAP | Donaldson | Acquired via trade | SPR | | After |
| 7/12/2023 | CAP | Kemp | Traded away | SPR | | After |
| 7/12/2023 | CAP | Waldichuk | Traded away | OLL | | After |
| 7/12/2023 | CLE | Adams,R | Acquired via trade | OLL | | After |
| 7/12/2023 | CLE | Brieske | Traded away | OLL | | After |
| 7/12/2023 | CLE | Brown,S | Traded away | OLL | | After |
| 7/12/2023 | CLE | Cobb | Traded away | OLL | | After |
| 7/12/2023 | CLE | Floro | Traded away | OLL | | After |
| 7/12/2023 | CLE | Garcia,J | Acquired via trade | OLL | | After |
| 7/12/2023 | CLE | Greinke | Acquired via trade | OLL | | After |
| 7/12/2023 | CLE | Leiter | Acquired via trade | OLL | | After |
| 7/12/2023 | CLE | Lux | Traded away | OLL | | After |
| 7/12/2023 | CLE | Megill,Ty | Acquired via trade | OLL | | After |
| 7/12/2023 | CLE | Segura | Acquired via trade | OLL | | After |
| 7/12/2023 | DUR | Azocar | Traded away | TOR | | After |
| 7/12/2023 | DUR | Ruf | Acquired via trade | TOR | | After |
| 7/12/2023 | OLL | Adams,R | Traded away | CLE | | After |
| 7/12/2023 | OLL | Bote | Traded away | CAP | | After |
| 7/12/2023 | OLL | Brieske | Acquired via trade | CLE | | After |
| 7/12/2023 | OLL | Brown,S | Acquired via trade | CLE | | After |
| 7/12/2023 | OLL | Cobb | Acquired via trade | CLE | | After |
| 7/12/2023 | OLL | Floro | Acquired via trade | CLE | | After |
| 7/12/2023 | OLL | Garcia,J | Traded away | CLE | | After |
| 7/12/2023 | OLL | Greinke | Traded away | CLE | | After |
| 7/12/2023 | OLL | Leiter | Traded away | CLE | | After |
| 7/12/2023 | OLL | Lux | Acquired via trade | CLE | | After |
| 7/12/2023 | OLL | Megill,Ty | Traded away | CLE | | After |
| 7/12/2023 | OLL | Segura | Traded away | CLE | | After |
| 7/12/2023 | OLL | Waldichuk | Acquired via trade | CAP | | After |
| 7/12/2023 | SPR | Donaldson | Traded away | CAP | | After |
| 7/12/2023 | SPR | Kemp | Acquired via trade | CAP | | After |
| 7/12/2023 | TOR | Azocar | Acquired via trade | DUR | | After |
| 7/12/2023 | TOR | Ruf | Traded away | DUR | | After |
| 7/13/2023 | CAP | Bote | Promoted to active roster | | | Before |
| 7/13/2023 | CAP | Sale | Demoted to reserve roster | | | Before |
| 7/13/2023 | CLE | Garcia,Ro | Promoted to active roster | | | Before |
| 7/13/2023 | CLE | Greinke | Demoted to reserve roster | | | Before |
| 7/13/2023 | CLE | Megill,Ty | Demoted to reserve roster | | | Before |
| 7/13/2023 | CLE | Olivares | Demoted to reserve roster | | | Before |
| 7/13/2023 | CLE | Raley,L | Promoted to active roster | | | Before |
| 7/13/2023 | CLE | Walsh,Jar | Promoted to active roster | | | Before |
| 7/13/2023 | OLL | Alberto | Demoted to reserve roster | | | Before |
| 7/13/2023 | OLL | Brieske | Activated from Injured List | | | Before |
| 7/13/2023 | OLL | Loup | Promoted to active roster | | | Before |
| 7/13/2023 | PRO | Severino,L | Placed on Injured List | | 7/12/2023 | Before |
| 7/13/2023 | PRO | Syndergaard | Promoted to active roster | | | Before |
| 7/13/2023 | PUE | Biggio | Placed on Injured List | | 7/13/2023 | Before |
| 7/13/2023 | PUE | Bush | Promoted to active roster | | | Before |
| 7/13/2023 | PUE | Duran,Jh | Activated from Injured List | | | Before |
| 7/13/2023 | PUE | Hentges | Placed on Injured List | | 7/13/2023 | Before |
| 7/13/2023 | PUE | Lewis,R | Promoted to active roster | | | Before |
| 7/13/2023 | PUE | Weissert | Demoted to reserve roster | | | Before |
| 7/16/2023 | CAL | deGrom | Promoted to active roster | | | Before |
| 7/16/2023 | CAL | Pilkington | Demoted to reserve roster | | | Before |
| 7/16/2023 | NHP | Almonte,Y | Demoted to reserve roster | | | Before |
| 7/16/2023 | NHP | Mills,W | Promoted to active roster | | | Before |
| 7/16/2023 | OLL | Alzolay | Promoted to active roster | | | Before |
| 7/16/2023 | OLL | Flexen | Activated from Injured List | | | Before |
| 7/16/2023 | OLL | Floro | Placed on Injured List | | 6/26/2023 | Before |
| 7/16/2023 | OLL | Smeltzer | Demoted to reserve roster | | | Before |
| 7/16/2023 | OLL | Verlander | Placed on Injured List | | 7/15/2023 | Before |
| 7/16/2023 | PUE | Gonzalez,O | Promoted to active roster | | | Before |
| 7/16/2023 | PUE | Jones,N | Demoted to reserve roster | | | Before |
| 7/16/2023 | PUE | Marsh | Placed on Injured List | | 7/15/2023 | Before |
| 7/16/2023 | PUE | Pujols | Promoted to active roster | | | Before |
| 7/16/2023 | PUE | Vosler | Demoted to reserve roster | | | Before |
| 7/16/2023 | PUE | Wisdom | Activated from Injured List | | | Before |
| 7/16/2023 | TOR | Azocar | Promoted to active roster | | | Before |
| 7/16/2023 | TOR | Kelly,J | Promoted to active roster | | | Before |
| 7/16/2023 | TOR | Luzardo | Demoted to reserve roster | | | Before |
| 7/16/2023 | TOR | Thompson,T | Demoted to reserve roster | | | Before |
| 7/18/2023 | AUR | Arroyo | Traded away | HAV | | After |
| 7/18/2023 | AUR | Calhoun,W | Traded away | RMH | | After |
| 7/18/2023 | AUR | Devers | Acquired via trade | HAV | | After |
| 7/18/2023 | AUR | Florial | Traded away | RMH | | After |
| 7/18/2023 | AUR | Gray,Jos | Acquired via trade | HAV | | After |
| 7/18/2023 | AUR | Grissom | Traded away | RMH | | After |
| 7/18/2023 | AUR | Machado,A | Acquired via trade | HAV | | After |
| 7/18/2023 | AUR | Mantiply | Traded away | RMH | | After |
| 7/18/2023 | AUR | Martinez,S | Acquired via trade | RMH | | After |
| 7/18/2023 | AUR | Miller,O | Acquired via trade | HAV | | After |
| 7/18/2023 | AUR | Moll | Acquired via trade | RMH | | After |
| 7/18/2023 | AUR | Mondesi | Traded away | RMH | | After |
| 7/18/2023 | AUR | Ohtani | Traded away | HAV | | After |
| 7/18/2023 | AUR | Perez,Ci | Acquired via trade | RMH | | After |
| 7/18/2023 | AUR | Romano | Traded away | HAV | | After |
| 7/18/2023 | AUR | Steele | Acquired via trade | RMH | | After |
| 7/18/2023 | AUR | Torrens | Traded away | RMH | | After |
| 7/18/2023 | AUR | Winckowski | Acquired via trade | HAV | | After |
| 7/18/2023 | CAP | Fried | Acquired via trade | DUR | | After |
| 7/18/2023 | CAP | Hill,G | Traded away | DUR | | After |
| 7/18/2023 | CAP | Meyers | Traded away | DUR | | After |
| 7/18/2023 | CAP | Peralta,D | Acquired via trade | DUR | | After |
| 7/18/2023 | CAP | Rodriguez,Ed | Traded away | DUR | | After |
| 7/18/2023 | CHI | Alberto | Acquired via trade | OLL | | After |
| 7/18/2023 | CHI | Vogt | Traded away | OLL | | After |
| 7/18/2023 | CLE | Garcia,Ro | Traded away | HAV | | After |
| 7/18/2023 | CLE | Higgins | Traded away | HAV | | After |
| 7/18/2023 | CLE | Knizner | Acquired via trade | HAV | | After |
| 7/18/2023 | DUR | Farmer,K | Traded away | HAV | | After |
| 7/18/2023 | DUR | Fletcher,D | Traded away | TOR | | After |
| 7/18/2023 | DUR | Fried | Traded away | CAP | | After |
| 7/18/2023 | DUR | Hedges | Traded away | HAV | | After |
| 7/18/2023 | DUR | Hill,G | Acquired via trade | CAP | | After |
| 7/18/2023 | DUR | Lynn | Traded away | TOR | | After |
| 7/18/2023 | DUR | Meyers | Acquired via trade | CAP | | After |
| 7/18/2023 | DUR | Moran,J | Traded away | TOR | | After |
| 7/18/2023 | DUR | Peralta,D | Traded away | CAP | | After |
| 7/18/2023 | DUR | Rodriguez,Ed | Acquired via trade | CAP | | After |
| 7/18/2023 | DUR | Rojas,M | Traded away | HAV | | After |
| 7/18/2023 | DUR | Romano | Acquired via trade | HAV | | After |
| 7/18/2023 | DUR | Rosario,Ed | Acquired via trade | TOR | | After |
| 7/18/2023 | DUR | Serven | Acquired via trade | HAV | | After |
| 7/18/2023 | DUR | Smith-Njigba | Acquired via trade | TOR | | After |
| 7/18/2023 | DUR | Winker | Acquired via trade | TOR | | After |
| 7/18/2023 | HAV | Arroyo | Acquired via trade | AUR | | After |
| 7/18/2023 | HAV | Devers | Traded away | AUR | | After |
| 7/18/2023 | HAV | Farmer,K | Acquired via trade | DUR | | After |
| 7/18/2023 | HAV | Garcia,Ro | Acquired via trade | CLE | | After |
| 7/18/2023 | HAV | Gray,Jos | Traded away | AUR | | After |
| 7/18/2023 | HAV | Hedges | Acquired via trade | DUR | | After |
| 7/18/2023 | HAV | Higgins | Acquired via trade | CLE | | After |
| 7/18/2023 | HAV | Knizner | Traded away | CLE | | After |
| 7/18/2023 | HAV | Machado,A | Traded away | AUR | | After |
| 7/18/2023 | HAV | Miller,O | Traded away | AUR | | After |
| 7/18/2023 | HAV | Ohtani | Acquired via trade | AUR | | After |
| 7/18/2023 | HAV | Rojas,M | Acquired via trade | DUR | | After |
| 7/18/2023 | HAV | Romano | Traded away | DUR | | After |
| 7/18/2023 | HAV | Romano | Acquired via trade | AUR | | After |
| 7/18/2023 | HAV | Serven | Traded away | DUR | | After |
| 7/18/2023 | HAV | Winckowski | Traded away | AUR | | After |
| 7/18/2023 | OLL | Alberto | Traded away | CHI | | After |
| 7/18/2023 | OLL | Vogt | Acquired via trade | CHI | | After |
| 7/18/2023 | PEA | Cave | Acquired via trade | TOR | | After |
| 7/18/2023 | PEA | Fletcher,D | Acquired via trade | TOR | | After |
| 7/18/2023 | PEA | Haniger | Acquired via trade | TOR | | After |
| 7/18/2023 | PEA | Quijada | Traded away | TOR | | After |
| 7/18/2023 | PEA | Suarez,J | Acquired via trade | TOR | | After |
| 7/18/2023 | PEA | Taylor,C | Traded away | TOR | | After |
| 7/18/2023 | RMH | Calhoun,W | Acquired via trade | AUR | | After |
| 7/18/2023 | RMH | Florial | Acquired via trade | AUR | | After |
| 7/18/2023 | RMH | Grissom | Acquired via trade | AUR | | After |
| 7/18/2023 | RMH | Mantiply | Acquired via trade | AUR | | After |
| 7/18/2023 | RMH | Martinez,S | Traded away | AUR | | After |
| 7/18/2023 | RMH | Moll | Traded away | AUR | | After |
| 7/18/2023 | RMH | Mondesi | Acquired via trade | AUR | | After |
| 7/18/2023 | RMH | Perez,Ci | Traded away | AUR | | After |
| 7/18/2023 | RMH | Steele | Traded away | AUR | | After |
| 7/18/2023 | RMH | Torrens | Acquired via trade | AUR | | After |
| 7/18/2023 | TOR | Cave | Traded away | PEA | | After |
| 7/18/2023 | TOR | Fletcher,D | Traded away | PEA | | After |
| 7/18/2023 | TOR | Fletcher,D | Acquired via trade | DUR | | After |
| 7/18/2023 | TOR | Haniger | Traded away | PEA | | After |
| 7/18/2023 | TOR | Lynn | Acquired via trade | DUR | | After |
| 7/18/2023 | TOR | Moran,J | Acquired via trade | DUR | | After |
| 7/18/2023 | TOR | Quijada | Acquired via trade | PEA | | After |
| 7/18/2023 | TOR | Rosario,Ed | Traded away | DUR | | After |
| 7/18/2023 | TOR | Smith-Njigba | Traded away | DUR | | After |
| 7/18/2023 | TOR | Suarez,J | Traded away | PEA | | After |
| 7/18/2023 | TOR | Taylor,C | Acquired via trade | PEA | | After |
| 7/18/2023 | TOR | Winker | Traded away | DUR | | After |
| 7/19/2023 | AUR | Jansen,D | Promoted to active roster | | | Before |
| 7/19/2023 | AUR | Martinez,S | Promoted to active roster | | | Before |
| 7/19/2023 | AUR | Narvaez | Demoted to reserve roster | | | Before |
| 7/19/2023 | AUR | Woodford | Demoted to reserve roster | | | Before |
| 7/19/2023 | CAP | Cabrera,E | Demoted to reserve roster | | | Before |
| 7/19/2023 | CAP | Foley | Activated from Injured List | | | Before |
| 7/19/2023 | CAP | Manaea | Activated from Injured List | | | Before |
| 7/19/2023 | CAP | Voit | Demoted to reserve roster | | | Before |
| 7/19/2023 | CLE | Adams,R | Promoted to active roster | | | Before |
| 7/19/2023 | CLE | Greinke | Promoted to active roster | | | Before |
| 7/19/2023 | CLE | Knizner | Demoted to reserve roster | | | Before |
| 7/19/2023 | DUR | Meyers | Promoted to active roster | | | Before |
| 7/19/2023 | DUR | Rodriguez,Ed | Activated from Injured List | | | Before |
| 7/19/2023 | DUR | Winker | Demoted to reserve roster | | | Before |
| 7/19/2023 | HAV | Arroyo | Promoted to active roster | | | Before |
| 7/19/2023 | HAV | Garcia,Ro | Demoted to reserve roster | | | Before |
| 7/19/2023 | HAV | Hedges | Demoted to reserve roster | | | Before |
| 7/19/2023 | HAV | Higgins | Demoted to reserve roster | | | Before |
| 7/19/2023 | HAV | Voth | Demoted to reserve roster | | | Before |
| 7/19/2023 | NHP | Nelson,R | Promoted to active roster | | | Before |
| 7/19/2023 | NHP | Peralta,F | Demoted to reserve roster | | | Before |
| 7/19/2023 | PEA | Fletcher,D | Promoted to active roster | | | Before |
| 7/19/2023 | PEA | Friedl | Demoted to reserve roster | | | Before |
| 7/19/2023 | PEA | Garver | Demoted to reserve roster | | | Before |
| 7/19/2023 | PEA | Wynns | Promoted to active roster | | | Before |
| 7/19/2023 | PUE | Gonzalez,O | Demoted to reserve roster | | | Before |
| 7/19/2023 | PUE | Jones,N | Promoted to active roster | | | Before |
| 7/19/2023 | PUE | Pujols | Demoted to reserve roster | | | Before |
| 7/19/2023 | PUE | Vosler | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Calhoun,W | Demoted to reserve roster | | | Before |
| 7/19/2023 | RMH | Calhoun,W | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Castro,W | Demoted to reserve roster | | | Before |
| 7/19/2023 | RMH | Contreras,R | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Florial | Demoted to reserve roster | | | Before |
| 7/19/2023 | RMH | Florial | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Kelly,C | Demoted to reserve roster | | | Before |
| 7/19/2023 | RMH | Meneses | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Mondesi | Demoted to reserve roster | | | Before |
| 7/19/2023 | RMH | Mondesi | Promoted to active roster | | | Before |
| 7/19/2023 | RMH | Torrens | Promoted to active roster | | | Before |
| 7/22/2023 | CAP | Story | Placed on Injured List | | 7/21/2023 | Before |
| 7/22/2023 | CAP | Voit | Promoted to active roster | | | Before |
| 7/22/2023 | CLE | Greinke | Demoted to reserve roster | | | Before |
| 7/22/2023 | CLE | Lambert | Promoted to active roster | | | Before |
| 7/22/2023 | DUR | Bader | Promoted to active roster | | | Before |
| 7/22/2023 | DUR | Hill,G | Demoted to reserve roster | | | Before |
| 7/22/2023 | DUR | Jackson,Z | Demoted to reserve roster | | | Before |
| 7/22/2023 | DUR | Meyers | Demoted to reserve roster | | | Before |
| 7/22/2023 | DUR | Ruf | Promoted to active roster | | | Before |
| 7/22/2023 | DUR | Serven | Promoted to active roster | | | Before |
| 7/22/2023 | HAV | Bride | Demoted to reserve roster | | | Before |
| 7/22/2023 | HAV | Higgins | Promoted to active roster | | | Before |
| 7/22/2023 | NHP | Nelson,R | Demoted to reserve roster | | | Before |
| 7/22/2023 | NHP | Otto | Promoted to active roster | | | Before |
| 7/22/2023 | OLL | Dickerson,C | Demoted to reserve roster | | | Before |
| 7/22/2023 | OLL | Ward | Activated from Injured List | | | Before |
| 7/22/2023 | RMH | Ortiz,LF | Promoted to active roster | | | Before |
| 7/22/2023 | RMH | Refsnyder | Demoted to reserve roster | | | Before |
| 7/22/2023 | SPR | Houser | Activated from Injured List | | | Before |
| 7/22/2023 | SPR | Thompson,Zach | Demoted to reserve roster | | | Before |
| 7/22/2023 | TOR | Casali | Demoted to reserve roster | | | Before |
| 7/22/2023 | TOR | Higashioka | Promoted to active roster | | | Before |
| 7/25/2023 | CAP | Sale | Promoted to active roster | | | Before |
| 7/25/2023 | CAP | Voit | Demoted to reserve roster | | | Before |
| 7/25/2023 | CLE | Eflin | Promoted to active roster | | | Before |
| 7/25/2023 | CLE | Hicks,J | Placed on Injured List | | 7/23/2023 | Before |
| 7/25/2023 | DSP | Pena | Activated from Injured List | | | Before |
| 7/25/2023 | DSP | Toro | Demoted to reserve roster | | | Before |
| 7/25/2023 | OLL | Alzolay | Demoted to reserve roster | | | Before |
| 7/25/2023 | OLL | Floro | Activated from Injured List | | | Before |
| 7/25/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | Azocar | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | Carpenter,M | Promoted to active roster | | | Before |
| 7/25/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 7/25/2023 | TOR | Casali | Promoted to active roster | | | Before |
| 7/25/2023 | TOR | Higashioka | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | Jimenez,E | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | Kelly,J | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 7/25/2023 | TOR | Luzardo | Promoted to active roster | | | Before |
| 7/25/2023 | TOR | Marte,K | Demoted to reserve roster | | | Before |
| 7/25/2023 | TOR | Thompson,T | Promoted to active roster | | | Before |
| 7/28/2023 | AUR | Lauer | Placed on Injured List | | 7/15/2023 | Before |
| 7/28/2023 | AUR | Morris | Promoted to active roster | | | Before |
| 7/28/2023 | CED | Banks | Demoted to reserve roster | | | Before |
| 7/28/2023 | CED | Brujan | Promoted to active roster | | | Before |
| 7/28/2023 | CED | Gilbreath | Promoted to active roster | | | Before |
| 7/28/2023 | CED | Holderman | Promoted to active roster | | | Before |
| 7/28/2023 | CED | Kinley | Placed on Injured List | | 7/28/2023 | Before |
| 7/28/2023 | CED | McKenna | Placed on Injured List | | 7/25/2023 | Before |
| 7/28/2023 | CLE | Hummel | Promoted to active roster | | | Before |
| 7/28/2023 | CLE | Raley,L | Demoted to reserve roster | | | Before |
| 7/28/2023 | CUY | Casas | Promoted to active roster | | | Before |
| 7/28/2023 | CUY | Heasley | Placed on Injured List | | 7/24/2023 | Before |
| 7/28/2023 | CUY | Patino | Promoted to active roster | | | Before |
| 7/28/2023 | CUY | Reynolds,M | Demoted to reserve roster | | | Before |
| 7/28/2023 | DSP | German,D | Promoted to active roster | | | Before |
| 7/28/2023 | DSP | May,D | Demoted to reserve roster | | | Before |
| 7/28/2023 | OLL | Dickerson,C | Promoted to active roster | | | Before |
| 7/28/2023 | OLL | Ward | Placed on Injured List | | 7/28/2023 | Before |
| 7/28/2023 | PUE | Biggio | Activated from Injured List | | | Before |
| 7/28/2023 | PUE | Bush | Demoted to reserve roster | | | Before |
| 7/28/2023 | PUE | Hentges | Activated from Injured List | | | Before |
| 7/28/2023 | PUE | Lewis,R | Demoted to reserve roster | | | Before |
| 7/31/2023 | CAL | Pilkington | Promoted to active roster | | | Before |
| 7/31/2023 | CAP | Fried | Activated from Injured List | | | Before |
| 7/31/2023 | CAP | Pasquantino | Demoted to reserve roster | | | Before |
| 7/31/2023 | CAP | Sale | Demoted to reserve roster | | | Before |
| 7/31/2023 | CAP | Voit | Promoted to active roster | | | Before |
| 7/31/2023 | OLL | Junis | Activated from Injured List | | | Before |
| 7/31/2023 | OLL | Loup | Demoted to reserve roster | | | Before |
| 7/31/2023 | OLL | Ray | Demoted to reserve roster | | | Before |
| 7/31/2023 | OLL | Verlander | Activated from Injured List | | | Before |
| 8/3/2023 | CED | Carpenter,K | Demoted to reserve roster | | | Before |
| 8/3/2023 | CED | Hall,Da | Promoted to active roster | | | Before |
| 8/3/2023 | CED | Newman | Demoted to reserve roster | | | Before |
| 8/3/2023 | CED | Smith,K | Promoted to active roster | | | Before |
| 8/3/2023 | CLE | Eflin | Demoted to reserve roster | | | Before |
| 8/3/2023 | CLE | Greinke | Promoted to active roster | | | Before |
| 8/3/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 8/3/2023 | TOR | Azocar | Promoted to active roster | | | Before |
| 8/3/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 8/3/2023 | TOR | Luzardo | Demoted to reserve roster | | | Before |
| 8/6/2023 | AUR | Bouchard | Promoted to active roster | | | Before |
| 8/6/2023 | AUR | Call | Demoted to reserve roster | | | Before |
| 8/6/2023 | AUR | Lauer | Activated from Injured List | | | Before |
| 8/6/2023 | AUR | Morris | Demoted to reserve roster | | | Before |
| 8/6/2023 | CLE | Leiter | Placed on Injured List | | 8/4/2023 | Before |
| 8/6/2023 | CLE | Megill,Ty | Promoted to active roster | | | Before |
| 8/6/2023 | DCM | Bethancourt | Demoted to reserve roster | | | Before |
| 8/6/2023 | DCM | Huff | Promoted to active roster | | | Before |
| 8/6/2023 | DCM | Stashak | Promoted to active roster | | | Before |
| 8/6/2023 | DCM | Strzelecki | Demoted to reserve roster | | | Before |
| 8/6/2023 | DCM | Wong,C | Promoted to active roster | | | Before |
| 8/6/2023 | DCM | Zavala | Placed on Injured List | | 7/28/2023 | Before |
| 8/6/2023 | DSP | Anderson,C | Demoted to reserve roster | | | Before |
| 8/6/2023 | DSP | Matzek | Promoted to active roster | | | Before |
| 8/6/2023 | DUR | Gray,Jon | Activated from Injured List | | | Before |
| 8/6/2023 | DUR | Paddack | Demoted to reserve roster | | | Before |
| 8/6/2023 | NHP | Hill,T | Placed on Injured List | | 8/5/2023 | Before |
| 8/6/2023 | NHP | Smith,P | Promoted to active roster | | | Before |
| 8/6/2023 | OLL | Hand | Promoted to active roster | | | Before |
| 8/6/2023 | OLL | Miranda | Placed on Injured List | | 8/6/2023 | Before |
| 8/6/2023 | PUE | Jones,N | Demoted to reserve roster | | | Before |
| 8/6/2023 | PUE | Marsh | Activated from Injured List | | | Before |
| 8/6/2023 | RMH | Bradish | Promoted to active roster | | | Before |
| 8/6/2023 | RMH | Gore,M | Placed on Injured List | | 8/1/2023 | Before |
| 8/6/2023 | RMH | Refsnyder | Promoted to active roster | | | Before |
| 8/6/2023 | RMH | Robert | Placed on Injured List | | 7/17/2023 | Before |
| 8/6/2023 | TOR | Brown,H | Promoted to active roster | | | Before |
| 8/6/2023 | TOR | Carpenter,M | Demoted to reserve roster | | | Before |
| 8/6/2023 | TOR | Casali | Demoted to reserve roster | | | Before |
| 8/6/2023 | TOR | Higashioka | Promoted to active roster | | | Before |
| 8/6/2023 | TOR | Jimenez,E | Promoted to active roster | | | Before |
| 8/6/2023 | TOR | Kelly,J | Promoted to active roster | | | Before |
| 8/6/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 8/6/2023 | TOR | Lynn | Demoted to reserve roster | | | Before |
| 8/6/2023 | TOR | Marte,K | Promoted to active roster | | | Before |
| 8/6/2023 | TOR | Paredes,I | Placed on Injured List | | 8/4/2023 | Before |
| 8/9/2023 | CAP | Bote | Placed on Injured List | | 8/4/2023 | Before |
| 8/9/2023 | CAP | Peraza | Promoted to active roster | | | Before |
| 8/9/2023 | CLE | Hensley | Promoted to active roster | | | Before |
| 8/9/2023 | CLE | Hicks,J | Activated from Injured List | | | Before |
| 8/9/2023 | CLE | Hummel | Demoted to reserve roster | | | Before |
| 8/9/2023 | CLE | Megill,Ty | Demoted to reserve roster | | | Before |
| 8/9/2023 | CLE | Olivares | Demoted to reserve roster | | | Before |
| 8/9/2023 | CLE | Olivares | Promoted to active roster | | | Before |
| 8/9/2023 | CLE | Olivares | Promoted to active roster | | | Before |
| 8/9/2023 | CLE | Raley,L | Demoted to reserve roster | | | Before |
| 8/9/2023 | CLE | Raley,L | Promoted to active roster | | | Before |
| 8/9/2023 | CLE | Walsh,Jar | Demoted to reserve roster | | | Before |
| 8/9/2023 | CUY | Curry | Promoted to active roster | | | Before |
| 8/9/2023 | CUY | Escobar,E | Promoted to active roster | | | Before |
| 8/9/2023 | CUY | Garrett,S | Promoted to active roster | | | Before |
| 8/9/2023 | CUY | Larnach | Demoted to reserve roster | | | Before |
| 8/9/2023 | CUY | Leblanc | Promoted to active roster | | | Before |
| 8/9/2023 | CUY | Rendon | Demoted to reserve roster | | | Before |
| 8/9/2023 | CUY | Ryan | Placed on Injured List | | 8/9/2023 | Before |
| 8/9/2023 | CUY | Walls | Demoted to reserve roster | | | Before |
| 8/9/2023 | PEA | Borucki | Promoted to active roster | | | Before |
| 8/9/2023 | PEA | Grossman | Activated from Injured List | | | Before |
| 8/9/2023 | PEA | Heaney | Demoted to reserve roster | | | Before |
| 8/9/2023 | PEA | Hernandez,Ya | Demoted to reserve roster | | | Before |
| 8/9/2023 | PEA | Snell | Activated from Injured List | | | Before |
| 8/9/2023 | PEA | Yarbrough | Demoted to reserve roster | | | Before |
| 8/12/2023 | CAP | Ferguson | Demoted to reserve roster | | | Before |
| 8/12/2023 | CAP | Sale | Promoted to active roster | | | Before |
| 8/12/2023 | DSP | Hudson,Dan | Demoted to reserve roster | | | Before |
| 8/12/2023 | DSP | Rogers,Ty | Promoted to active roster | | | Before |
| 8/12/2023 | HAV | Houck | Placed on Injured List | | 8/12/2023 | Before |
| 8/12/2023 | HAV | Sawamura | Promoted to active roster | | | Before |
| 8/12/2023 | HOL | Hill,D | Promoted to active roster | | | Before |
| 8/12/2023 | HOL | Rodriguez,Ju | Placed on Injured List | | 8/11/2023 | Before |
| 8/12/2023 | PUE | Biggio | Demoted to reserve roster | | | Before |
| 8/12/2023 | PUE | Gonzalez,O | Promoted to active roster | | | Before |
| 8/12/2023 | PUE | Pujols | Promoted to active roster | | | Before |
| 8/12/2023 | PUE | Vosler | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | Azocar | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | Carpenter,M | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | Jimenez,E | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | Kelly,J | Demoted to reserve roster | | | Before |
| 8/12/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Luzardo | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Lynn | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Manning | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Manoah | Placed on Injured List | | 8/11/2023 | Before |
| 8/12/2023 | TOR | Mayza | Promoted to active roster | | | Before |
| 8/12/2023 | TOR | Quijada | Placed on Injured List | | 8/12/2023 | Before |
| 8/15/2023 | CED | Cabrera,M | Promoted to active roster | | | Before |
| 8/15/2023 | CED | Hall,Da | Demoted to reserve roster | | | Before |
| 8/15/2023 | CLE | Ashcraft | Placed on Injured List | | 8/12/2023 | Before |
| 8/15/2023 | CLE | Megill,Ty | Promoted to active roster | | | Before |
| 8/15/2023 | CUY | Heasley | Activated from Injured List | | | Before |
| 8/15/2023 | CUY | Patino | Demoted to reserve roster | | | Before |
| 8/15/2023 | DSP | Pena | Placed on Injured List | | 8/15/2023 | Before |
| 8/15/2023 | DSP | Pollock | Placed on Injured List | | 8/14/2023 | Before |
| 8/15/2023 | DSP | Solak | Promoted to active roster | | | Before |
| 8/15/2023 | DSP | Toro | Promoted to active roster | | | Before |
| 8/15/2023 | OLL | Hand | Demoted to reserve roster | | | Before |
| 8/15/2023 | OLL | Ward | Activated from Injured List | | | Before |
| 8/15/2023 | PRO | Capel | Promoted to active roster | | | Before |
| 8/15/2023 | PRO | Fraley | Demoted to reserve roster | | | Before |
| 8/15/2023 | PRO | Severino,L | Activated from Injured List | | | Before |
| 8/15/2023 | PRO | Syndergaard | Demoted to reserve roster | | | Before |
| 8/15/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 8/15/2023 | TOR | Brown,H | Demoted to reserve roster | | | Before |
| 8/15/2023 | TOR | Greene,H | Promoted to active roster | | | Before |
| 8/15/2023 | TOR | Lynn | Demoted to reserve roster | | | Before |
| 8/18/2023 | CAP | Hall,DL | Placed on Injured List | | 8/18/2023 | Before |
| 8/18/2023 | CAP | Herrera,I | Promoted to active roster | | | Before |
| 8/18/2023 | CLE | Greinke | Demoted to reserve roster | | | Before |
| 8/18/2023 | CLE | Leiter | Activated from Injured List | | | Before |
| 8/18/2023 | HOL | Karinchak | Demoted to reserve roster | | | Before |
| 8/18/2023 | HOL | Puk | Promoted to active roster | | | Before |
| 8/18/2023 | OLL | Dickerson,C | Demoted to reserve roster | | | Before |
| 8/18/2023 | OLL | Miranda | Activated from Injured List | | | Before |
| 8/18/2023 | TOR | Casali | Promoted to active roster | | | Before |
| 8/18/2023 | TOR | Higashioka | Demoted to reserve roster | | | Before |
| 8/18/2023 | TOR | Kelly,J | Promoted to active roster | | | Before |
| 8/18/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 8/21/2023 | NHP | Kershaw | Demoted to reserve roster | | | Before |
| 8/21/2023 | NHP | Velazquez,N | Promoted to active roster | | | Before |
| 8/21/2023 | OLL | Hand | Promoted to active roster | | | Before |
| 8/21/2023 | OLL | Verlander | Placed on Injured List | | 8/19/2023 | Before |
| 8/21/2023 | SPR | Candelario | Placed on Injured List | | 8/10/2023 | Before |
| 8/21/2023 | SPR | Odor | Promoted to active roster | | | Before |
| 8/21/2023 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 8/21/2023 | TOR | Kelly,J | Demoted to reserve roster | | | Before |
| 8/21/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 8/21/2023 | TOR | Lynn | Promoted to active roster | | | Before |
| 8/24/2023 | DUR | Brennan | Promoted to active roster | | | Before |
| 8/24/2023 | DUR | Mitchell,G | Demoted to reserve roster | | | Before |
| 8/24/2023 | DUR | Serven | Placed on Injured List | | 8/22/2023 | Before |
| 8/24/2023 | DUR | Stephenson,T | Demoted to reserve roster | | | Before |
| 8/24/2023 | DUR | Taveras | Promoted to active roster | | | Before |
| 8/24/2023 | DUR | Winker | Promoted to active roster | | | Before |
| 8/24/2023 | HOL | Loaisiga | Promoted to active roster | | | Before |
| 8/24/2023 | HOL | Scherzer | Demoted to reserve roster | | | Before |
| 8/24/2023 | OLL | Brieske | Demoted to reserve roster | | | Before |
| 8/24/2023 | OLL | Smeltzer | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Azocar | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 8/24/2023 | TOR | Casali | Demoted to reserve roster | | | Before |
| 8/24/2023 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 8/24/2023 | TOR | Greene,H | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Higashioka | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Jimenez,E | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Lynn | Promoted to active roster | | | Before |
| 8/24/2023 | TOR | Paredes,I | Activated from Injured List | | | Before |
| 8/24/2023 | TOR | Taylor,C | Demoted to reserve roster | | | Before |
| 8/24/2023 | TOR | Thompson,T | Demoted to reserve roster | | | Before |
| 8/24/2023 | TOR | Whitlock | Demoted to reserve roster | | | Before |
| 8/27/2023 | CED | Albies | Demoted to reserve roster | | | Before |
| 8/27/2023 | CED | Espinal,S | Placed on Injured List | | 8/22/2023 | Before |
| 8/27/2023 | CED | Gilbreath | Demoted to reserve roster | | | Before |
| 8/27/2023 | CED | Kinley | Activated from Injured List | | | Before |
| 8/27/2023 | CED | Marcano | Promoted to active roster | | | Before |
| 8/27/2023 | CED | Newman | Promoted to active roster | | | Before |
| 8/27/2023 | CLE | Adams,R | Demoted to reserve roster | | | Before |
| 8/27/2023 | CLE | Knizner | Demoted to reserve roster | | | Before |
| 8/27/2023 | CLE | Knizner | Promoted to active roster | | | Before |
| 8/27/2023 | CLE | Knizner | Promoted to active roster | | | Before |
| 8/27/2023 | CLE | Leiter | Demoted to reserve roster | | | Before |
| 8/27/2023 | CLE | Meyer | Promoted to active roster | | | Before |
| 8/27/2023 | CLE | Moniak | Promoted to active roster | | | Before |
| 8/27/2023 | CLE | Nootbaar | Demoted to reserve roster | | | Before |
| 8/27/2023 | DCM | Carrasco | Placed on Injured List | | 8/21/2023 | Before |
| 8/27/2023 | DCM | Kuhl | Promoted to active roster | | | Before |
| 8/27/2023 | DSP | Pena | Activated from Injured List | | | Before |
| 8/27/2023 | DSP | Urias,L | Placed on Injured List | | 8/26/2023 | Before |
| 8/27/2023 | PUE | Hernandez,T | Placed on Injured List | | 8/26/2023 | Before |
| 8/27/2023 | PUE | Jones,N | Promoted to active roster | | | Before |
| 8/27/2023 | TOR | Azocar | Demoted to reserve roster | | | Before |
| 8/27/2023 | TOR | Gray,S | Demoted to reserve roster | | | Before |
| 8/27/2023 | TOR | Lynn | Demoted to reserve roster | | | Before |
| 8/27/2023 | TOR | Manoah | Activated from Injured List | | | Before |
| 8/27/2023 | TOR | Marte,K | Demoted to reserve roster | | | Before |
| 8/27/2023 | TOR | Taylor,C | Promoted to active roster | | | Before |
| 8/27/2023 | TOR | Thompson,T | Promoted to active roster | | | Before |
| 8/27/2023 | TOR | Whitlock | Promoted to active roster | | | Before |
| 8/30/2023 | AUR | Canha | Placed on Injured List | | 8/30/2023 | Before |
| 8/30/2023 | AUR | Mathias | Promoted to active roster | | | Before |
| 8/30/2023 | CAP | Hall,DL | Activated from Injured List | | | Before |
| 8/30/2023 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 8/30/2023 | CAP | Jameson | Promoted to active roster | | | Before |
| 8/30/2023 | CAP | Peraza | Demoted to reserve roster | | | Before |
| 8/30/2023 | CAP | Sale | Demoted to reserve roster | | | Before |
| 8/30/2023 | CAP | Story | Activated from Injured List | | | Before |
| 8/30/2023 | CLE | Alfaro | Demoted to reserve roster | | | Before |
| 8/30/2023 | CLE | Burleson | Promoted to active roster | | | Before |
| 8/30/2023 | CLE | Greinke | Promoted to active roster | | | Before |
| 8/30/2023 | CLE | Hensley | Demoted to reserve roster | | | Before |
| 8/30/2023 | CLE | Hummel | Promoted to active roster | | | Before |
| 8/30/2023 | CLE | Oviedo | Demoted to reserve roster | | | Before |
| 8/30/2023 | CUY | Escobar,E | Demoted to reserve roster | | | Before |
| 8/30/2023 | CUY | Garrett,S | Demoted to reserve roster | | | Before |
| 8/30/2023 | CUY | Rendon | Promoted to active roster | | | Before |
| 8/30/2023 | CUY | Reynolds,M | Promoted to active roster | | | Before |
| 8/30/2023 | CUY | Ryan | Activated from Injured List | | | Before |
| 8/30/2023 | CUY | Thompson,M | Demoted to reserve roster | | | Before |
| 8/30/2023 | HAV | Arroyo | Placed on Injured List | | 8/29/2023 | Before |
| 8/30/2023 | HAV | Bride | Promoted to active roster | | | Before |
| 8/30/2023 | OLL | Dickerson,C | Promoted to active roster | | | Before |
| 8/30/2023 | OLL | Ward | Placed on Injured List | | 8/30/2023 | Before |
| 9/2/2023 | CAP | Bote | Activated from Injured List | | | Before |
| 9/2/2023 | CAP | Fried | Placed on Injured List | | 9/2/2023 | Before |
| 9/2/2023 | CLE | Adams,R | Promoted to active roster | | | Before |
| 9/2/2023 | CLE | Alfaro | Promoted to active roster | | | Before |
| 9/2/2023 | CLE | Greinke | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Hensley | Promoted to active roster | | | Before |
| 9/2/2023 | CLE | Hicks,J | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Keller,B | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Lodolo | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Megill,Ty | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Neris | Demoted to reserve roster | | | Before |
| 9/2/2023 | CLE | Nootbaar | Promoted to active roster | | | Before |
| 9/2/2023 | CLE | Raley,L | Promoted to active roster | | | Before |
| 9/2/2023 | CLE | Walsh,Jar | Promoted to active roster | | | Before |
| 9/2/2023 | DSP | Pollock | Activated from Injured List | | | Before |
| 9/2/2023 | DSP | Solak | Demoted to reserve roster | | | Before |
| 9/2/2023 | DUR | Castillo,D | Demoted to reserve roster | | | Before |
| 9/2/2023 | DUR | Thompson,R | Promoted to active roster | | | Before |
| 9/2/2023 | HOL | Celestino | Promoted to active roster | | | Before |
| 9/2/2023 | HOL | Knebel | Demoted to reserve roster | | | Before |
| 9/2/2023 | HOL | Kopech | Demoted to reserve roster | | | Before |
| 9/2/2023 | HOL | Ragans | Promoted to active roster | | | Before |
| 9/2/2023 | HOL | Trivino | Promoted to active roster | | | Before |
| 9/2/2023 | HOL | Turner,J | Demoted to reserve roster | | | Before |
| 9/2/2023 | NHP | Hill,T | Activated from Injured List | | | Before |
| 9/2/2023 | NHP | Velazquez,N | Demoted to reserve roster | | | Before |
| 9/2/2023 | SPR | Bello | Placed on Injured List | | 9/2/2023 | Before |
| 9/2/2023 | SPR | Thompson,Zach | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Anderson,I | Demoted to reserve roster | | | Before |
| 9/2/2023 | TOR | Azocar | Demoted to reserve roster | | | Before |
| 9/2/2023 | TOR | Azocar | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Casali | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Gray,S | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Higashioka | Demoted to reserve roster | | | Before |
| 9/2/2023 | TOR | King,M | Promoted to active roster | | | Before |
| 9/2/2023 | TOR | Milner | Demoted to reserve roster | | | Before |
| 9/2/2023 | TOR | Thompson,T | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Almora | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Alvarado | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Banks | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Barrero | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Barria | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Bieber | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Brash | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Brosseau | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Bubic | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Cabrera,M | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Carpenter,K | Promoted to active roster | | | Before |
| 9/5/2023 | CED | De Los Santos,E | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | De Los Santos,Y | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Diaz,Alex | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Diaz,Yai | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Freeland | Activated from Injured List | | | Before |
| 9/5/2023 | CED | Gilbreath | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Gustave | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Hall,Da | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Happ | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Hays | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Kinley | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Kirby | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Lamet | Promoted to active roster | | | Before |
| 9/5/2023 | CED | McKenna | Activated from Injured List | | | Before |
| 9/5/2023 | CED | Myers | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Nola,Aa | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Palacios,R | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Sanchez,G | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Solano | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Tepera | Demoted to reserve roster | | | Before |
| 9/5/2023 | CED | Thompson,Zack | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Tovar | Promoted to active roster | | | Before |
| 9/5/2023 | CED | Vogelbach | Demoted to reserve roster | | | Before |
| 9/5/2023 | CLE | Greinke | Promoted to active roster | | | Before |
| 9/5/2023 | CLE | Hicks,J | Promoted to active roster | | | Before |
| 9/5/2023 | CLE | Kim | Demoted to reserve roster | | | Before |
| 9/5/2023 | CLE | Leiter | Promoted to active roster | | | Before |
| 9/5/2023 | CLE | Olson | Demoted to reserve roster | | | Before |
| 9/5/2023 | CLE | Segura | Demoted to reserve roster | | | Before |
| 9/5/2023 | HOL | Contreras,WJ | Demoted to reserve roster | | | Before |
| 9/5/2023 | HOL | McCann | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Aguilar,J | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Arcia | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Baddoo | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Banuelos | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Bassitt | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Blackburn | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Brantley | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Bumgarner | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Camargo | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Cessa | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Crismatt | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Cruz,N | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Garcia,Av | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Harper | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Hjelle | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Lorenzen | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Martinez,N | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Mejia,F | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Nelson,K | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Nola,Au | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Peralta,Wa | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Perez,Ma | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Pham | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Rizzo | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Ryu | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Stanton | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Valdez,F | Demoted to reserve roster | | | Before |
| 9/5/2023 | NDF | Vargas,I | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Varland | Promoted to active roster | | | Before |
| 9/5/2023 | NDF | Zimmermann | Promoted to active roster | | | Before |
| 9/5/2023 | NHP | Cabrera,O | Demoted to reserve roster | | | Before |
| 9/5/2023 | NHP | Phillips,B | Promoted to active roster | | | Before |
| 9/5/2023 | OLL | Floro | Placed on Injured List | | 9/5/2023 | Before |
| 9/5/2023 | OLL | Jansen,K | Placed on Injured List | | 9/5/2023 | Before |
| 9/5/2023 | OLL | Loup | Promoted to active roster | | | Before |
| 9/5/2023 | OLL | Ray | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Aquino | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Biggio | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Burnes | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Bush | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Campusano | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Cisnero | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Cruz,F | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Duran,Jh | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Gallen | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Garrett,A | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Gomes | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Gonsolin | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Gonzalez,O | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Grove | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Hentges | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Hudson,Dak | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Iglesias,J | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Kingery | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Lewis,R | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Marsh | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Musgrove | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Overton | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Plawecki | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Pujols | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Schmidt | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Schwarber | Demoted to reserve roster | | | Before |
| 9/5/2023 | PUE | Tarnok | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Vosler | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Weissert | Promoted to active roster | | | Before |
| 9/5/2023 | PUE | Wisdom | Demoted to reserve roster | | | Before |
| 9/5/2023 | TOR | Anderson,I | Promoted to active roster | | | Before |
| 9/5/2023 | TOR | Azocar | Promoted to active roster | | | Before |
| 9/5/2023 | TOR | Brown,H | Promoted to active roster | | | Before |
| 9/5/2023 | TOR | Carpenter,M | Demoted to reserve roster | | | Before |
| 9/5/2023 | TOR | Carroll | Demoted to reserve roster | | | Before |
| 9/5/2023 | TOR | Gray,S | Demoted to reserve roster | | | Before |
| 9/5/2023 | TOR | Luzardo | Demoted to reserve roster | | | Before |
| 9/5/2023 | TOR | Marte,K | Promoted to active roster | | | Before |
| 9/8/2023 | CAP | Peralta,D | Placed on Injured List | | 9/6/2023 | Before |
| 9/8/2023 | CAP | Peraza | Promoted to active roster | | | Before |
| 9/8/2023 | DSP | Cabrera,G | Promoted to active roster | | | Before |
| 9/8/2023 | DSP | Martin,Ch | Demoted to reserve roster | | | Before |
| 9/8/2023 | DUR | Ahmed | Promoted to active roster | | | Before |
| 9/8/2023 | DUR | Chisholm | Demoted to reserve roster | | | Before |
| 9/8/2023 | DUR | Marinaccio | Demoted to reserve roster | | | Before |
| 9/8/2023 | DUR | Murphy,T | Promoted to active roster | | | Before |
| 9/8/2023 | DUR | Outman | Promoted to active roster | | | Before |
| 9/8/2023 | DUR | Sears | Promoted to active roster | | | Before |
| 9/8/2023 | DUR | Taveras | Demoted to reserve roster | | | Before |
| 9/8/2023 | DUR | Winker | Demoted to reserve roster | | | Before |
| 9/8/2023 | HAV | McCarthy | Demoted to reserve roster | | | Before |
| 9/8/2023 | HAV | Rojas,M | Promoted to active roster | | | Before |
| 9/8/2023 | OLL | Molina | Placed on Injured List | | 9/8/2023 | Before |
| 9/8/2023 | OLL | Vogt | Promoted to active roster | | | Before |
| 9/11/2023 | CAL | Baz | Promoted to active roster | | | Before |
| 9/11/2023 | CAL | Chargois | Demoted to reserve roster | | | Before |
| 9/11/2023 | CAL | Garcia,M | Demoted to reserve roster | | | Before |
| 9/11/2023 | CAL | Lopez,O | Promoted to active roster | | | Before |
| 9/11/2023 | CAL | Naylor,B | Promoted to active roster | | | Before |
| 9/11/2023 | CAL | Pilkington | Demoted to reserve roster | | | Before |
| 9/11/2023 | CAL | Ruiz,E | Promoted to active roster | | | Before |
| 9/11/2023 | CAL | Thaiss | Demoted to reserve roster | | | Before |
| 9/11/2023 | CAL | Votto | Placed on Injured List | | 9/7/2023 | Before |
| 9/11/2023 | CLE | Adams,R | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Ashcraft | Activated from Injured List | | | Before |
| 9/11/2023 | CLE | Chapman,A | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Duran,E | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Garcia,J | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Hensley | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Keller,B | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Kim | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Knizner | Placed on Injured List | | 9/6/2023 | Before |
| 9/11/2023 | CLE | Lambert | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Leiter | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Leiter | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Lodolo | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Megill,Ty | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Meyer | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Neris | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Olivares | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Olson | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Ottavino | Demoted to reserve roster | | | Before |
| 9/11/2023 | CLE | Oviedo | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Segura | Promoted to active roster | | | Before |
| 9/11/2023 | CLE | Wisler | Demoted to reserve roster | | | Before |
| 9/11/2023 | DSP | German,D | Demoted to reserve roster | | | Before |
| 9/11/2023 | DSP | Solak | Promoted to active roster | | | Before |
| 9/11/2023 | HOL | Diaz,Ed | Demoted to reserve roster | | | Before |
| 9/11/2023 | HOL | Graterol | Promoted to active roster | | | Before |
| 9/11/2023 | HOL | Hilliard | Promoted to active roster | | | Before |
| 9/11/2023 | HOL | Lyles | Promoted to active roster | | | Before |
| 9/11/2023 | HOL | Rodon | Demoted to reserve roster | | | Before |
| 9/11/2023 | HOL | Williams,D | Demoted to reserve roster | | | Before |
| 9/11/2023 | NHP | Abrams | Promoted to active roster | | | Before |
| 9/11/2023 | NHP | Cavalli | Promoted to active roster | | | Before |
| 9/11/2023 | NHP | Fedde | Promoted to active roster | | | Before |
| 9/11/2023 | NHP | Groshans | Promoted to active roster | | | Before |
| 9/11/2023 | NHP | Hoerner | Demoted to reserve roster | | | Before |
| 9/11/2023 | NHP | Luplow | Promoted to active roster | | | Before |
| 9/11/2023 | NHP | Machado,M | Demoted to reserve roster | | | Before |
| 9/11/2023 | NHP | Slater | Demoted to reserve roster | | | Before |
| 9/11/2023 | NHP | Springs | Demoted to reserve roster | | | Before |
| 9/11/2023 | NHP | Strider | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Assad | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Bregman | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Castillo,DA | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Franco,W | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Gaddis | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Lavastida | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Realmuto | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Singer | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Steer | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Syndergaard | Promoted to active roster | | | Before |
| 9/11/2023 | PRO | Taillon | Demoted to reserve roster | | | Before |
| 9/11/2023 | PRO | Webb | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Carroll | Promoted to active roster | | | Before |
| 9/11/2023 | TOR | Casali | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Higashioka | Promoted to active roster | | | Before |
| 9/11/2023 | TOR | King,M | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Milner | Promoted to active roster | | | Before |
| 9/11/2023 | TOR | Moran,J | Promoted to active roster | | | Before |
| 9/11/2023 | TOR | Quijada | Activated from Injured List | | | Before |
| 9/11/2023 | TOR | Quijada | Demoted to reserve roster | | | Before |
| 9/11/2023 | TOR | Stephenson,R | Promoted to active roster | | | Before |
| 9/11/2023 | TOR | Whitlock | Demoted to reserve roster | | | Before |
| 9/14/2023 | DSP | Lopez,P | Demoted to reserve roster | | | Before |
| 9/14/2023 | DSP | May,D | Promoted to active roster | | | Before |